Results 81 to 90 of about 398,878 (275)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Upper Bounds on the Signed Total (K, K)-Domatic Number of Graphs
Discussiones Mathematicae Graph Theory, 2015 Let G be a graph with vertex set V (G), and let f : V (G) → {−1, 1} be a two-valued function. If k ≥ 1 is an integer and Σx∈N(v) f(x) ≥ k for each v ∈ V (G), where N(v) is the neighborhood of v, then f is a signed total k-dominating function on G. A set {
Volkmann Lutz
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Domination Parameters of a Graph and its Complement
Discussiones Mathematicae Graph Theory, 2018 A dominating set in a graph G is a set S of vertices such that every vertex in V (G) \ S is adjacent to at least one vertex in S, and the domination number of G is the minimum cardinality of a dominating set of G.
Desormeaux Wyatt J. +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Cubic Graphs with Total Domatic Number at Least Two
Discussiones Mathematicae Graph Theory, 2018 Let G be a graph with no isolated vertex. A total dominating set of G is a set S of vertices of G such that every vertex is adjacent to at least one vertex in S.
Akbari Saieed +3 more
doaj +1 more source
The complexity of connected domination and total domination by restricted induced graphs [PDF]
, 2010 Given a graph class C, it is natural to ask whether a given graph has a connected or a total dominating set inducing a graph of C and, if so, what is the minimal size of such a set.
Schaudt, Oliver, Schrader, Rainer
core
On the number of minimum dominating sets and total dominating sets in forests
Journal of Graph TheoryAbstractWe show that the maximum number of minimum dominating sets of a forest with domination number is at most and construct for each a tree with domination number that has more than minimum dominating sets. Furthermore, we disprove a conjecture about the number of minimum total dominating sets in forests by Henning, Mohr and Rautenbach.
Jan Petr, Julien Portier, Leo Versteegen
openaire +4 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source