Results 91 to 100 of about 11,901,808 (241)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Vertices Contained In All Or In No Minimum Semitotal Dominating Set Of A Tree
Discussiones Mathematicae Graph Theory, 2016 Let G be a graph with no isolated vertex. In this paper, we study a parameter that is squeezed between arguably the two most important domination parameters; namely, the domination number, γ(G), and the total domination number, γt(G). A set S of vertices
Henning Michael A., Marcon Alister J.
doaj +1 more source
On the maximum number of minimum total dominating sets in forests
Discrete Mathematics & Theoretical Computer Science, 2019 We propose the conjecture that every tree with order $n$ at least $2$ and total domination number $\gamma_t$ has at most $\left(\frac{n-\frac{\gamma_t}{2}}{\frac{\gamma_t}{2}}\right)^{\frac{\gamma_t}{2}}$ minimum total dominating sets. As a relaxation of this conjecture, we show that every forest $F$ with order $n$, no isolated vertex, and total ...
Henning, Michael A. +2 more
openaire +5 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Total $k$-distance domination critical graphs [PDF]
Transactions on Combinatorics, 2016 A set $S$ of vertices in a graph $G=(V,E)$ is called a total$k$-distance dominating set if every vertex in $V$ is withindistance $k$ of a vertex in $S$.
Doost Ali Mojdeh +3 more
doaj
Maximizing lifetime of connected-dominating-set in cognitive radio networks
, 2012 Maximizing lifetime of connected-dominating-set in cognitive radio ...
I Stojmenovic (13639189) +4 more
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source