Results 111 to 120 of about 398,878 (275)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
On the Total k-Domination in Graphs
Discussiones Mathematicae Graph Theory, 2018 Let G = (V, E) be a graph; a set S ⊆ V is a total k-dominating set if every vertex v ∈ V has at least k neighbors in S. The total k-domination number γkt(G) is the minimum cardinality among all total k-dominating sets.
Bermudo Sergio +2 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
k-Tuple total domination and Mycieleskian graphs [PDF]
Transactions on Combinatorics, 2012 Let $k$ be a positive integer. A subset $S$ of $V(G)$ in a graph $G$ is a $k$-tuple total dominating set of $G$ if every vertex of $G$ has at least $k$ neighbors in $S$.
Adel P. Kazemi
doaj
Disjoint total Restrained Dominating sets in Graphs [PDF]
Journal of Ultra Scientist of Physical Sciences Section A, 2020 V. R. KULLI, B. CHALUVARAJU, M. KUMARA
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Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
On the Total Dominating Set of ${3}/{2}$-Generated Groups
Armenian Journal of MathematicsA subset $S$ of a group $G$ is called a total dominating set of $G$ if for any nontrivial element $x\in G$ there is an element $y\in S$ such that $G =\left< x, y\right> $. Tarski monsters, constructed by Olshanskii, are infinite simple groups, any pair of non-commuting elements of which is a total dominating set.
Atabekyan, Varujan S., Aslanyan, Haik T.
openaire +2 more sources