Results 121 to 130 of about 11,901,808 (241)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
k-Tuple total domination and Mycieleskian graphs [PDF]
Transactions on Combinatorics, 2012 Let $k$ be a positive integer. A subset $S$ of $V(G)$ in a graph $G$ is a $k$-tuple total dominating set of $G$ if every vertex of $G$ has at least $k$ neighbors in $S$.
Adel P. Kazemi
doaj
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Domination parameters of a graph with added vertex [PDF]
Opuscula Mathematica, 2004 Let \(G=(V,E)\) be a graph. A subset \(D\subseteq V\) is a total dominating set of \(G\) if for every vertex \(y\in V\) there is a vertex \(x\in D\) with \(xy\in E\).
Maciej Zwierzchowski
doaj
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Construction of a fault tolerance connected dominating set in wireless sensor network
, 2009 In wireless sensor networks, virtual backbone has been proposed as the routing infrastructure to alleviate the broadcasting storm problem and perform some other tasks such as area monitoring.
Yu HB(于海斌) +2 more
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Locating Total Dominating Sets in the Join, Corona and Composition of Graphs
, 2014 which is also a total dominating set is called a locating total dominating set of G. The minimum cardinality of a locating total dominating set of G is called the locating total domination number of G.
Benjamin N Omamalin +2 more
core