Results 131 to 140 of about 43,787 (293)

k-Tuple total domination and Mycieleskian graphs [PDF]

Transactions on Combinatorics, 2012
Let $k$ be a positive integer. A subset $S$ of $V(G)$ in a graph $G$ is a $k$-tuple total dominating set of $G$ if every vertex of $G$ has at least $k$ neighbors in $S$.
Adel P. Kazemi
doaj  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

ANALISA LOCATING TOTAL DOMINATING SET PADA GRAF KHUSUS DAN GRAF HASIL OPERASI AMALGAMAS [PDF]

, 2017
Teori graf pertama kalo dikenalkan pada tahun 1735 oleh seorang matematikawan bernama Leonhard Euler yang berasal dari Swiss. Teori graf merupakan salah satu cabang matematika diskrit yang digunakan untuk menggambarkan suatu persoalan agar lebih mudah
SARI, Masnita Novita
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Progress towards the two-thirds conjecture on locating-total dominating sets [PDF]

We study upper bounds on the size of optimum locating-total dominating sets in graphs. A set $S$ of vertices of a graph $G$ is a locating-total dominating set if every vertex of $G$ has a neighbor in $S$, and if any two vertices outside $S$ have distinct
Chakraborty, Dipayan, Hakanen, Anni, Henning, Michael, Foucaud, Florent, Wagler, Annegret, Henning, Michael A., Wagler, Annegret K.   +6 more
core   +2 more sources

Lower Bounds for the Total Distance $k$-Domination Number of a Graph

Theory and Applications of Graphs
For $k \geq 1$ and a graph $G$ without isolated vertices, a \emph{total distance $k$-dominating set} of $G$ is a set of vertices $S \subseteq V(G)$ such that every vertex in $G$ is within distance $k$ to some vertex of $S$ other than itself.
Randy R. Davila
doaj   +1 more source