Results 141 to 150 of about 7,042,445 (296)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
The [a,b]-domination and [a,b]-total Domination of Graphs
, 2017 A subset $S$ of the vertices of $G = (V, E)$ is an $[a, b]$-set if for every vertex $v$ not in $S$ we have the number of neighbors of $v$ in $S$ is between $a$ and $b$ for non-negative integers $a$ and $b$, that is, every vertex $v$ not in $S$ is ...
Xiujun Zhang, Zehui Shao, Hong Yang
core +1 more source
Signed total strong Roman domination in graphs [PDF]
Discrete Mathematics Letters, 2022 Maryam Hajjari +1 more
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Nordhaus-Gaddum Type Results for Total Domination
, 2011 Graph TheoryInternational audienceA Nordhaus-Gaddum-type result is a (tight) lower or upper bound on the sum or product of a parameter of a graph and its complement. In this paper we study Nordhaus-Gaddum-type results for total domination. We examine the
Michael Henning +5 more
core +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Total roman domination in digraphs
, 2021 Let D be a nite and simple digraph with vertex set V (D). A Roman dominating function (RDF) on a digraph D is a function f : V (D) → {0; 1; 2} satisfying the condition that every vertex v with f(v) = 0 has an in-neighbor u with f(u) = 2. The weight of an
Zhuang, Wei, Hu, Kangxiu, Hao, Guoliang
core
Proper total domination in graphs [PDF]
Electronic Journal of MathematicsRitabrato Chatterjee +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source