Results 121 to 130 of about 369,294 (274)
Partial Total Domination in Hypergraphs
MathematicsThis paper establishes fundamental results for partial total domination in hypergraphs. We present tight bounds for the partial total domination number in k-uniform hypergraphs, demonstrate relationships with classical domination parameters, and provide ...
Abdulkafi Sanad, Chaoqian Li
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Proper total domination in graphs [PDF]
Electronic Journal of MathematicsRitabrato Chatterjee +3 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Domination integrity of total graphs
, 2014 The domination integrity of a simple connected graph G is a measure of vulnerability of a graph. Here we determine the domination integrity of total graphs of path Pn, cycle Cn and star K1,n.
VAİDYA, S. K., SHAH, N. H.
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Total domination in cubic Kn��del graphs
, 2018 A subset $D$ of vertices of a graph $G$ is a \textit{dominating set} if for each $u\in V(G)\setminus D$, $u$ is adjacent to some vertex $v\in D$. The \textit{dominating number}, $ (G)$ of $G$, is the minimum cardinality of a dominating set of $G$. A set $D\subseteq V(G)$ is a \textit{total dominating set} if for each $u\in V(G)$, $u$ is adjacent to ...
Jafari Rad, Nader +3 more
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Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source