Results 41 to 50 of about 266,223 (319)

Total knee arthroplasty: improving outcomes with a multidisciplinary approach

Journal of Multidisciplinary Healthcare, 2018
Total knee arthroplasty (TKA) is the most commonly performed inpatient surgical procedure within the USA and is estimated to reach 3.48 million procedures annually by 2030.
James E. Feng, D. Novikov, A. Anoushiravani, R. Schwarzkopf   +3 more
semanticscholar   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Total knee replacement in patients with osteoarthritis and concomitant inveterate patellar dislocation

Arthroplasty Today, 2019
The inveterate patellar dislocation is an uncommon entity. The most frequent findings correspond to a misaligned valgus associated with lateral patellar dislocation.
David Figueroa, MD, Alan Garín, MD, Francisco Figueroa, MD   +2 more
doaj   +1 more source

Knee Scores of Patients with Non‐Lateral Compartmental Knee Osteoarthritis Undergoing Mobile, Fixed‐Bearing Unicompartmental Knee and Total Knee Arthroplasties: A Randomized Controlled Trial

Orthopaedic Surgery, 2022
Objective To evaluate knee scores and clinical efficacies of patients with non‐lateral unicompartmental knee osteoarthritis (OA) who randomly underwent mobile‐bearing (MB) unicompartmental knee arthroplasty (UKA), fixed‐bearing (FB) UKA, and total knee ...
Li‐ping Wu, Hermann O Mayr, Xing Zhang, Yuan‐qiao Huang, Yuan‐zhuang Chen, Yu‐ming Li   +5 more
doaj   +1 more source

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

Advanced Science, EarlyView.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang, Yi Liu, Ziying Sun, Jia Li, Zhihao Lu, Jiayuan Huang, Shixian Hu, Peihua Cao, Xiaolong Cao, Shangru Li, Jianzhao Ruan, Jinhui Liu, Jingyu Xie, Haitao Sun, Tianyu Chen, Shengfa Li, Zhaohua Zhu, Zhibo Wen, Rocky S. Tuan, David John Hunter, Zhong Alan Li, Dongquan Shi, Changhai Ding   +22 more
wiley   +1 more source

Defining a successful total knee arthroplasty: a systematic review of metrics of clinically important changes [PDF]

, 2023
Zodina A. Beiene, Kira K. Tanghe, Cynthia A. Kahlenberg, Alexander S. McLawhorn, Catherine H. MacLean, Elizabeth B. Gausden   +5 more
openalex   +1 more source

The Comparison of Computer Navigation and Robotic-assisted Total Knee Arthroplasty: A Review of Current Literature

Formosan Journal of Musculoskeletal Disorders
This review aimed to assess the existing evidence regarding the comparison between robotic-assisted (RA) and computer navigation (CN) total knee arthroplasty (TKA). Our study commenced on August 25, 2023, utilizing a methodological approach that combined
Chia-Chun Hsia, De-Yi Liu, Nien-En Ku, Jui-Feng Chen, Shih-Chan Hsu, Shu-Jui Kuo   +5 more
doaj   +1 more source

Purtscher-like retinopathy following total knee arthroplasty: A report of 2 cases

American Journal of Ophthalmology Case Reports, 2020
Purpose: To describe two cases of Purtscher-like retinopathy after total knee arthroplasty. Observations: Two patients were referred for blurred vision after knee surgery.
Siyang Chaili, Audrey Mok, Sean D. Adrean   +2 more
doaj   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Total knee arthroplasty: A single centre review at 10 years of follow-up

Journal of Orthopaedics, Trauma and Rehabilitation, 2020
Background: Total knee arthroplasty is a common procedure for treatment of various non-infective arthritis. This study reviewed total knee arthroplasty cases up to 10 years of follow-up for the survival rate, reasons of revision and associated ...
Tao Sun Tycus Tse, Yik-Cheung Samuel Wan, Kin-Ho Leo Leung, Man-Kwan Wong   +3 more
doaj   +1 more source