Results 31 to 40 of about 133,754 (301)
Frontiers in Oncology, 2022 BackgroundPyrotinib, a small-molecule tyrosine kinase inhibitor, has been investigated as a component of neoadjuvant therapy in phase 2 trials of human epidermal growth factor receptor 2 (HER2)-positive breast cancer.
Xiaoyun Mao +11 more
doaj +1 more source
Magnetic resonance imaging tumor regression shrinkage patterns after neoadjuvant chemotherapy in patients with locally advanced breast cancer: correlation with tumor biological subtypes and pathological response after therapy [PDF]
, 2017 The objective of this study is to analyze magnetic resonance imaging shrinkage pattern of tumor regression after neoadjuvant chemotherapy and to evaluate its relationship with biological subtypes and pathological response.
Anastasi, Emanuela +6 more
core +1 more source
Total neoadjuvant therapy in oesophageal and gastro-oesophageal junctional adenocarcinoma
British Journal of Cancer, 2023 AbstractAdenocarcinoma of the oesophagus and gastro-oesophageal junction represent a large burden of cancer death in the Western World with an increasing incidence. In the past two decades, the overall survival of patients on a potentially curative treatment pathway has more than doubled due to the addition of perioperative oncological therapies to ...
Hollie A. Clements +2 more
openaire +3 more sources
Debating Pros and Cons of Total Neoadjuvant Therapy in Rectal Cancer [PDF]
Cancers, 2021 Recently, two large, randomised phase III clinical trials of total neoadjuvant therapy (TNT) in locally advanced rectal cancer were published (RAPIDO and PRODIGE 23). These two trials compared short-course radiotherapy (SCRT) followed by chemotherapy with standard chemoradiotherapy (CRT) and chemotherapy followed by CRT with standard CRT, respectively.
Sclafani, Francesco +2 more
openaire +3 more sources
Frontiers in Oncology, 2022 BackgroundGastrointestinal cancers are the most common malignant tumors worldwide. As the improvement of survival by surgical resection alone for cancers is close to the bottleneck, recent neoadjuvant therapy has been emphasized and applied in the ...
Xin-Yi Xu +7 more
doaj +1 more source
Initial experience of dedicated breast PET imaging of ER+ breast cancers using [F-18]fluoroestradiol. [PDF]
, 2019 Dedicated breast positron emission tomography (dbPET) is an emerging technology with high sensitivity and spatial resolution that enables detection of sub-centimeter lesions and depiction of intratumoral heterogeneity.
Chien, Amy J +10 more
core +2 more sources
Total neoadjuvant therapy in rectal cancer: the evidence and expectations
Critical Reviews in Oncology/Hematology, 2023 Current management of locally advanced rectal cancer achieves high cure rates, distant metastatic spread being the main cause of patients' death. Total neoadjuvant therapy (TNT) employs (chemo)radiotherapy and combined chemotherapy prior to surgery to improve the treatment outcomes.
Ludmila, Boublikova +3 more
openaire +2 more sources
Gut and Liver, 2022 Background/Aims: Controversy regarding the effectiveness of neoadjuvant therapy for resectable pancreatic ductal adenocarcinoma (PDAC) still exists.
Min Sung Yoon +14 more
doaj +1 more source
Neoadjuvant therapy for breast cancer [PDF]
, 2019 Objective: To evaluate the frequency of neoadjuvant therapy (NT) in women with stage I–III breast cancer in Italy and whether it is influenced by biological characteristics, screening history, and geographic area.
Carrozzi G. +10 more
core +1 more source
npj Breast Cancer, 2023 While overweight/obesity has become a major public health issue worldwide, any association between body mass index (BMI) and therapeutic response in neoadjuvant targeted therapy treated HER2 positive breast cancer patients remain unclear. The information
Lili Chen +17 more
doaj +1 more source