Results 191 to 200 of about 8,406,914 (282)

PD-1 deficiency reshapes the TCRβ repertoire and T-cell developmental programs associated with susceptibility to lupus-like autoimmunity. [PDF]

Front Immunol
Hou X, Liu Z, Lu G, Jiang S, Qiu J, Li C, Meng M, Hu Z, Lei Y, Lao H, Chen L, Wen Y, Xie S, Liang Y.   +13 more
europepmc   +1 more source

Genome‐wide identification of the bZIP transcription factor family in sainfoin (Onobrychis viciifolia Scop.) and expression profiles in response to aluminum stress

Grassland Research, EarlyView.
Sainfoin is an important forage legume with potential for cultivation in stressful environments, but its molecular response to aluminum toxicity remains unclear. This study identified 236 basic leucine zipper (bZIP) transcription factor genes in sainfoin and analyzed their evolutionary features and regulatory potential.
Peng Li, Hao Wen, Yiwei Bai, Jiachen Liu, Hui Wang, Yunwei Zhang   +5 more
wiley   +1 more source

Hydrogen excess drives metabolic reprogramming and viral dynamics in syngas-converting microbiomes. [PDF]

Environ Sci Ecotechnol
Ghiotto G, Francescato L, Biancalani MA, Treu L, Campanaro S.   +4 more
europepmc   +1 more source

Multi‐omics reveals gastrointestinal metabolic disorder‐induced diarrhea in postpartum dairy cows

iMetaOmics, EarlyView.
Nutritional diarrhea is a pervasive, costly challenge in dairy production. Using integrated metagenomic and metabolomic profiling, we identified coordinated microbial and metabolic alterations across the rumen, hindgut, and serum. In the rumen, enrichment of Prevotella sp.
Weixuan Tang, Yangyi Hao, Jiawei Zhang, Yajing Wang, Zhijun Cao, Hongjian Yang, Wei Wang, Shengli Li   +7 more
wiley   +1 more source

Effects of replacing extruded soybean meal with Periplaneta americana residue on laying performance, egg quality, and ovarian transcriptomic profiles in Guangxi Yao chickens. [PDF]

Poult Sci
Yan L, Yang M, Zi S, Jiao D, Jia X, Zhao T, Li H.   +6 more
europepmc   +1 more source

Lactobacillus johnsonii attenuates ovarian aging by remodeling the gut–ovary axis

iMetaOmics, EarlyView.
Aging is accompanied by a reduced abundance of L. johnsonii and ovarian decline. Supplementation with L. johnsonii elevates microbial IPA production via the LdhA enzyme and commensal bacteria. IPA activates the AhR/YAP signaling axis, promoting YAP nuclear translocation and inducing the expression of downstream target genes CYR61 and CTGF. This cascade
Jiamin He, Qiwen Wang, Luyi Chen, Yadong Qi, Dingjiacheng Jia, Jilei Xu, Qingyi Wang, Yao Jiang, Jian Zhou, Yong Sun, Ruochen Yan, Lan Wang, Tongyao Hou, Zheng Kuang, Min Jin, Liangjing Wang, Shujie Chen   +16 more
wiley   +1 more source

Effects of Dietary Digestible Energy Levels on Milk Performance, Rumen Fermentation, and Rumen Microbiota in Lactating Bactrian Camels from Southern Xinjiang. [PDF]

Animals (Basel)
Shao KY, Han F, Chen PH, Zhu HB, Liu BR, Xu M, Liu LL.   +6 more
europepmc   +1 more source

Lactobacillus derived small RNAs protect against Klebsiella pneumoniae infection

iMeta, EarlyView.
This study reveals that plant‐derived natural products confer protection against carbapenem‐resistant Klebsiella pneumoniae (CRKP) infection via remodeling the gut microbiota, with Lactobacillus identified as the core beneficial genus. Mechanistically, Lactobacillus murinus (L.
Tingting Xu, Xiuying Tao, Dan Fang, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +5 more
wiley   +1 more source

Metabolomic insights into inter-familial and pre-transport treatment effects on live transport stress in selectively-bred mussels, Perna canaliculus. [PDF]

Metabolomics
Cheng MCF, Zamora LN, Delorme NJ, Ragg NLC, Hickey AJR, Dunphy BJ.   +5 more
europepmc   +1 more source

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

iNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang, Shuang Wu, Shuangbiao Wei, Weizhen Xiang, Jianshang Huang, Lei Xiong, Hua Wang, Li Zuo   +7 more
wiley   +1 more source