Results 201 to 210 of about 8,406,914 (282)

Integorated multi-omics reveals the NOS2-metabolite-microbiota regulatory axis underlying feed efficiency in laying hens. [PDF]

Poult Sci
Hao D, Li H, Liu W, Shang G, Sun Y, Zhou Y, Wang J, Cao D, Che C, Li F.   +9 more
europepmc   +1 more source

Perceived Educational Value of a Self‐Developed 3D‐Printed Pediatric Dentistry Simulator

Journal of Dental Education, EarlyView.
ABSTRACT Purpose To design and assess a 3D‐printed pediatric dentistry simulator and to evaluate its perceived educational value and realism through student and expert feedback. Methods A maxillary simulator that is mountable on phantom heads was developed and produced by desktop stereolithography with single‐use inserts, enabling proximal caries ...
Michel Benyamin, Sandrella Hamdan, Timothy Fasham, Samuel Morice, Stephane Le Goff, Maria‐Antonietta D'Agostino, Marie Jannot, Yasmine Smail, Jean‐Pierre Attal, Hélène Gouze, Elisabeth Dursun, Philippe Francois   +11 more
wiley   +1 more source

Genetic dissection and transcriptomic analysis of a novel high-tillering phenotype in rice derived from weedy rice (Hapcheonaengmi3) and Tongil-type Rice (Milyang23). [PDF]

Plant Genome
Shim KC, Jeon D, Jeon YA, Adeva C, Lee HS, Kang JW, Park SE, Ahn SN, Park I.   +8 more
europepmc   +1 more source

Andrographolide Modulates Fibrogenic and Oxidative Stress Responses in Human Lung Fibroblasts

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pulmonary fibrosis is a progressive lung disorder characterized by fibroblast activation and excessive extracellular matrix deposition. Andrographolide (ANDRO) has been reported to attenuate pulmonary fibrosis, but the underlying molecular mechanisms remain incompletely understood.
Yu‐Hsin Tseng, Yen‐Hsien Wu, Yi‐Ching Liu, I‐Chen Chen, Chung‐Yu Yeh, Shang‐En Huang, Ren‐Long Jan, Jwu‐Lai Yeh, Jong‐Hau Hsu   +8 more
wiley   +1 more source

Microglia cause HIV-induced transcriptional and metabolic changes in human neural organoids. [PDF]

Commun Biol
Capendale PE, Helgers LC, Ambikan AT, Vieira de Sá R, Wolthers KC, Geijtenbeek TBH, Sridhar A, Neogi U, Pajkrt D.   +8 more
europepmc   +1 more source

The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu, Yang‐Shuai Wang, Chun‐Yang Shang, Ming Qi, Tong‐Chang Li, Li‐Xin Lian, Hai‐Quan Qiao   +6 more
wiley   +1 more source

ZPR1 Is Dispensable for HPV R-Loop Resolution but Regulates Host R-Loop Dynamics. [PDF]

Viruses
Moffitt R, Brooks S, Androphy EJ, DeSmet M.   +3 more
europepmc   +1 more source

DNA Immunotherapy (INO‐3107) Long‐Term Efficacy Supported by Enhanced Immunogenicity in HPV‐6/11 RRP

The Laryngoscope, EarlyView.
Adults with HPV‐6/11‐associated recurrent respiratory papillomatosis (RRP) received DNA immunotherapy INO‐3107 in a Phase 1/2 trial and were followed for one year, with additional clinical follow‐up in a long‐term extension. INO‐3107 was shown to generate increased HPV‐directed T‐cell responses in Year 1 and substantially reduced surgical procedures ...
Milan R. Amin, Peter C. Belafsky, Simon R. Best, Aaron D. Friedman, Adam M. Klein, David G. Lott, Ted Mau, Randal C. Paniello, Seth M. Pransky, Nabil F. Saba, Stefani A. Slog, Elisabeth Gillespie, Christopher Welsh, Michael Dallas, Matthew P. Morrow, Jeffrey M. Skolnik   +15 more
wiley   +1 more source

Host species-specific gene expression by a widespread and flexible chemosynthetic symbiont. [PDF]

ISME J
Kück AC, Leibrecht L, Morel-Letelier I, Gros O, Wilkins LGE, Yuen-Simović B, Petersen JM.   +6 more
europepmc   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source