Results 61 to 70 of about 3,883,670 (317)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Evolutionarily conserved herpesviral protein interaction networks. [PDF]

, 2009
Herpesviruses constitute a family of large DNA viruses widely spread in vertebrates and causing a variety of different diseases. They possess dsDNA genomes ranging from 120 to 240 kbp encoding between 70 to 170 open reading frames. We previously reported
Bandyopadhyay, Sourav, Baiker Armin, Brunn, Albrecht von, Dong, Yu-An, Silpa Suthram, Haas, Jürgen, Dietlind Rose, von Brunn, Albrecht, Rutenberg Christiane, Ralf Zimmer, Bailer Susanne M., Schmidt, Tina, Stellberger Thorsten, Rose, Dietlind, Haas Jürgen, Titz Björn, Zimmer, Ralf, Christine Zeretzke, Mareike Uhlmann, Seesandra V Rajagopala, Manfred Koegl, Boulet Hélène, Koegl, Manfred, Susanne M Bailer, Trey Ideker, Baiker, Armin, Fossum, Even, Zeretzke, Christine, Peter Uetz, Schmidt Tina, Koegl Manfred, Thorsten Stellberger, Hélène Boulet, Kraus Theo, Armin Baiker, Tina Schmidt, Ideker, Trey, Koszinowski, Ulrich, Sourav Bandyopadhyay, Suthram Silpa, Björn Titz, Boulet, Hélène, Koszinowski Ulrich, Rajagopala, Seesandra V., Caroline C Friedel, Bailer, Susanne M, Rajagopala, Seesandra V, Dong Yu-An, Even Fossum, Bandyopadhyay Sourav, Bailer, Susanne M., Uhlmann, Mareike, Haas, Jürgen G., Ulrich Koszinowski, Uhlmann Mareike, Uetz Peter, Zimmer Ralf, Christiane Rutenberg, Friedel, Caroline C., Friedel, Caroline C, Titz, Björn, Koszinowski, Ulrich H., Rajagopala Seesandra V., Titz, Bjoern, Haas, Juergen, Ideker Trey, Albrecht von Brunn, Suthram, Silpa, Zeretzke Christine, Rutenberg, Christiane, Kraus, Theo, Jürgen Haas, Friedel Caroline C., Stellberger, Thorsten, Theo Kraus, Yu-An Dong, Rose Dietlind, Fossum Even, Uetz, Peter, von Brunn Albrecht   +79 more
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CLINICAL AND LIQUOR DIFFERENCES IN CASES OF SEROUS AND PURULENT MENINGITIS IN CHILDREN OF DIFFERENT AGE

Детские инфекции (Москва), 2015
The article presents features of clinical course and composition of cerebrospinal liquid in cases of purulent and serous meningitis depending on the age of the patients and the disease etiology.
E. M. Mazayeva, L. A. Alekseyeva, N. V. Skripchenko, T. V. Bessonova   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Mutational analysis of the AtNUDT7 Nudix hydrolase from Arabidopsis thaliana reveals residues required for protein quaternary structure formation and activity. [PDF]

, 2009
Arabidopsis thaliana AtNUDT7, a homodimeric Nudix hydrolase active on ADP-ribose and NADH, exerts negative control on the major signaling complex involved in plant defense activation and programmed cell death.
Goch, Grażyna, Olejnik, Kamil, Grynberg, Marcin, Basińska, Teresa, Kraszewska, Elzbieta, Gruszecki, Wiesław I, Plochocka, Danuta   +6 more
core  

Interrogation of the protein-protein interactions between human BRCA2 BRC repeats and RAD51 reveals atomistic determinants of affinity

, 2011
The breast cancer suppressor BRCA2 controls the recombinase RAD51 in the reactions that mediate homologous DNA recombination, an essential cellular process required for the error-free repair of DNA double-stranded breaks.
Rajendra, Eason, Skylaris Chris-Kriton, Cole, Daniel J., Venkitaraman Ashok R., Hardwick, Bryn, Payne, Mike C., Mike C. Payne, McKenzie, Grahame J., Grahame J. McKenzie, Cole Daniel J., Mike C Payne, Hardwick Bryn, McKenzie Grahame J., Bryn Hardwick, Grahame J McKenzie, Ashok R Venkitaraman, Chris-Kriton Skylaris, Daniel J Cole, Ashok R. Venkitaraman, Eeson Rajendra, Roberts-Thomson Meredith, Skylaris, Chris-Kriton, Payne Mike C., Kowalczykowski, Stephen Charles, Venkitaraman, Ashok R., Rajendra Eeson, Roberts-Thomson, Meredith, Daniel J. Cole, Meredith Roberts-Thomson   +28 more
core   +1 more source

Albumin and total protein concentration - selected parameters of catabolic reaction and nutritional status among patients with craniocerebral injuries diagnosed with surgically treated cerebrovascular diseases

, 2021
Introduction: Posttraumatic metabolic disorders, including surgeries, generate a large energy expenditure in humans. They may lead to hypermetabolism, hypercatabolism, and hyperglycaemia, resulting in a severe condition of patients, which may require ...
Walewska, Elżbieta, Stanisław Wojtan, Maria Kózka, Staszkiewicz, Magdalena, Ścisło, Lucyna, Elżbieta Walewska, Wojtan, Stanisław, Paplaczyk, Małgorzata, Magdalena Staszkiewicz, Lucyna Ścisło, Małgorzata Paplaczyk, Kózka, Maria   +11 more
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BIOACTIVE COMPOUNDS AND ANTIOXIDANT ACTIVITY OF Rubus idaeus L. LEAVES

Acta Scientiarum Polonorum: Hortorum Cultus, 2018
In Poland, the genus Rubus comprises 95 species. Given the commercial production of the fruits as well as their medicinal properties and apicultural and ornamental importance, raspberries are commonly cultivated plants of great economic value.
Mirosława Chwil, Mikołaj Kostryco
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Salting the charged surface: pH and salt dependence of protein G B1 stability. [PDF]

, 2006
This study shows significant effects of protein surface charges on stability and these effects are not eliminated by salt screening. The stability for a variant of protein G B1 domain was studied in the pH-range of 1.5-11 at low, 0.15 M, and 2 M salt ...
Xue, Wei-Feng, Linse, Sara,, Bauer, Mikael C., Szczepankiewicz, Olga, Bauer, Mikael,, Lindman, Stina, Wei-Feng Xue, Xue, Wei-Feng,, Nilsson, Hanna,, Szczepankiewicz, Olga,, Stina Lindman, Olga Szczepankiewicz, Mikael C. Bauer, Hanna Nilsson, Lindman, Stina,, Nilsson, Hanna, Bauer, Mikael, Sara Linse, Linse, Sara, Lund University.   +19 more
core   +1 more source