Results 71 to 80 of about 8,388,417 (298)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Analytical aspects of spatially adapted total variation regularisation [PDF]
, 2016 In this paper we study the structure of solutions of the one dimensional weighted total variation regularisation problem, motivated by its application in signal recovery tasks.
Papafitsoros, Kostas +6 more
core +1 more source
Numerical solution to nonlinear Tricomi equation using WENO schemes
Electronic Journal of Differential Equations, 2010 Nonlinear Tricomi equation is a hybrid (hyperbolic-elliptic) second order partial differential equation, modelling the sonic boom focusing. In this paper, the Tricomi equation is transformed into a hyperbolic system of first order equations, in ...
Adrian Sescu +2 more
doaj
Nonlinear Interpolation and Total Variation Diminishing Schemes
, 2010 The Van Leer approach for the approximation of nonlinear scalar conservation laws is studied in one space dimension. The problem can be reduced to a nonlinear interpolation and we propose a convexity property for the interpolated values. We prove that under general hypotheses the method of lines in well posed in $\ ell^{\infty} \cap {\rm BV} $ and we ...
openaire +2 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Variation diminishing Hankel operators
, 2020 This paper studies the variation diminishing property of linear time-invariant Hankel k-positive systems, i.e., systems whose Hankel operator maps inputs with k - 1 sign changes to outputs with at most the same variation.
Sepulchre, R, Grussler, C, ,
core
Variation diminishing property with b = 1 p = 3 k = 1.
, 2016 Variation diminishing property with b = 1 p = 3 k = 1.
Abdul Majeed (725054) +2 more
core +1 more source
Introduction: Diminishing conflicts: Learning from the Asia-Pacific
, 2020 Diminishing conflicts? This book begins with ambiguity. It is intentional. By calling the book diminishing conflicts we mean not only to analyse conflict that has diminished in the Asia-Pacific region, but also to highlight lessons about what can be ...
Aspinall, Edward +2 more
core +1 more source
Analysis of Hypersonic Blunt-Body Flows Using a Total Variation Diminishing Scheme and the MacCormack Scheme [PDF]
, 1990 An explicit second-order accurate, total variation diminishing (TVD) scheme and the MacCormack scheme are applied to the Euler equations in axisymmetric form to study hypersonic blunt body flows. The modified flux approach of Harten, with modification by
Hughson, Montgomery C.
core +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source