Results 161 to 170 of about 58,366 (349)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Fascism as a recurring possibility: Zeev Sternhell, the anti-Enlightenment, and the intellectual history of European modernity. [PDF]
Hist Eur Ideas, 2023 Giordani T.
europepmc +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Hans Magnus Enzensberger und deutsche Philosophie
Brünner Beiträge zur Germanistik und Nordistik, 2016 First, this study deals with the problems that are connected with the reception of Enzensberger's works, second, it tries to put H. M. Enzensberger to the tradition of German postwar philosophy.
Aleš Urválek
doaj
Confucius, cyberpunk and Mr. Science: comparing AI ethics principles between China and the EU. [PDF]
AI Ethics, 2023 Fung P, Etienne H.
europepmc +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
War, threats of totalitarianism and national resistance in Ukraine: perspectives of Hannah Arendt and Anne Applebaum. [PDF]
Iryna Andrusiak
openalex +1 more source
Tracing Cold War in Post-Modern Management's Hot Issues [PDF]
Tracing Cold War in post-modern managerial science and ideology one encounters hot issues linking contemporary liberal dogmas and romanticized view of organizational leadership to the dismantling of a welfare state disguised as a liberation of an ...
Magala, S.J.
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source