Results 141 to 150 of about 58,366 (349)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Planet earth is knocking on the doctor's door. [PDF]

open access: yesPorto Biomed J, 2022
Haahtela T, Anto JM, Bousquet J.
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Luis Goytisolo’s \u3cem\u3eLa paradoja del ave migratoria\u3c/em\u3e as Postmodern Allegory: A Critique of Absolutism [PDF]

open access: yes, 2000
Luis Goytisolo’s short work of fiction, La paradoja del ave migratoria, was published in 1987 in a Post-Franco Spain and a Postmodern world. I will investigate this unusual novel as a postmodern allegory, relying on Brian McHale’s assertion that ...
Carney, Terri
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Missing social capital and the transition in Eastern Europe [PDF]

open access: yes
The transition of the »Old Communist« countries of East and Central Europe has been disappointingly slow given the amount of physical and human capital available at the start of the transition.
Paldam, Martin, Svendsen, Gert Tinggaard
core  

Cape Fear and Cuckoo’s Nest: Cultural Discourse on Dangerous Men [PDF]

open access: yes, 2012
Cape Fear, the movie, and Ken Kesey’s novel, One Flew Over the Cuckoo’s Nest, both debuted in 1962. The film, adapted by James Webb from John D. MacDonald’s 1957 crime fiction, The Executioners, was grounded in the cold war mentality of the 1950s.
Tanner, David
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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