Results 121 to 130 of about 7,929 (288)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

From totalitarianism from auto- totalitarianism : the vietnamese case

open access: yes, 2018
Ce travail est un prolongement des pensées de Hannah Arendt, de Vaclav Havel, de Deleuze-Guattari et d’autres chercheurs sur le totalitarisme dans l’analyse de la politique vietnamienne. Il ne prétend pas établir une définition personnelle et nouvelle du
Nguyen, Thi Tu Huy
core  

OFFRED AS THE VICTIM OF TOTALITARIANISM IN MARGARET ATWOOD’S THE HANDMAID’S TALE

open access: yes, 2019
This study uses a descriptive qualitative method which focusing on the literary work in the novel and interpretation on the analysis. The main data is taken from the novel The Handmaid’s Tale written by Margaret Atwood. This subject of study focus on the
TRANSISKA DEBORANTI, RIBKA
core   +1 more source

Planet earth is knocking on the doctor's door. [PDF]

open access: yesPorto Biomed J, 2022
Haahtela T, Anto JM, Bousquet J.
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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