Results 101 to 110 of about 58,366 (349)

Technical development and natural rights [PDF]

, 2012
Scientific and technical achievements can cause deep changes in spheres of morals and law. I am going to discuss some philosophical conclusions which follow from two significant ideas of contemporary civilization.
Nevvazhay, Igor
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Adult education, democracy, and totalitarianism

European Journal for Research on the Education and Learning of Adults
This article explores the role of adult education in supporting democracy through an examination of the former German Democratic Republic (GDR) (1949-1990).
Tetyana Hoggan-Kloubert, Chad Hoggan, Nicole Luthardt   +2 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Democracy, epistemic agency, and AI: political epistemology in times of artificial intelligence. [PDF]

AI Ethics, 2022
Coeckelbergh M.
europepmc   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Correlates and predictors of homonegativity among Mexican medical students

Interacciones, 2019
Background: The internalization of cultural homophobia as a rejection toward any internal and interpersonal aspect related to homosexuality can lead to intrapsychic conflicts and discrimination. This phenomenon when manifested in health professionals can
José Moral de Rubia, Adrián Valle de la O   +1 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

The Mystified Unknown—Sacralizing Influence in Soviet Science, Religion, and Ideology

Religions
This article investigates a distinctive discursive space within Soviet society where scientific inquiry and mystical thought coexisted, despite the state’s official commitment to atheism.
Maria Roginska
doaj   +1 more source

ALEXANDRE PALÉOLOGUE, DE LA SURVIE [PDF]

Diversitate si Identitate Culturala in Europa, 2011
Born an aristocrat, but above all, displaying an aristocratic constitution and vocation, Alexandru Paleologu is building a unique vision of Romania as a country laying under the pressure of an implacable history.
Dr. Ileana TĂNASE
doaj