Results 91 to 100 of about 11,544 (277)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

BOOK REVIEW: Peter Bernholz, ‟Totalitarianism, Terrorism and Supreme Values. History and Theory Cham”, Springer, 2017, 160 pp.

open access: yesStudia Universitatis Babeş-Bolyai. Studia Europaea, 2019
The book written by Peter Bernholz represents the culmination of a process, serving to refine his theory on the lexicographic preference for supreme values and its fundamental role in the ideologies of totalitarian regimes. As the author mentions in the
Mihai MURARIU
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Hannah Arendt and the political : the contemporary challenges posed by sovereignty, nationalism and imperialism [PDF]

open access: yes, 2015
This thesis seeks to show how the reassessment of Arendt’s thought for contemporary international political theory must be grounded in her first major published work, The Origins of Totalitarianism, and, more specifically, in the concept of the political
Nicholas, Donna
core   +1 more source

Correlates and predictors of homonegativity among Mexican medical students

open access: yesInteracciones, 2019
Background: The internalization of cultural homophobia as a rejection toward any internal and interpersonal aspect related to homosexuality can lead to intrapsychic conflicts and discrimination. This phenomenon when manifested in health professionals can
José Moral de Rubia   +1 more
doaj   +1 more source

Modern Dystopias and Theories of Totalitarianism [PDF]

open access: yes, 2013
The diploma thesis Modern Dystopias and Theories of Totalitarianism deals with comparation of this two phenomena. The thesis is based on the concept of Giovanni Sartori.
Machart, Filip
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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