Results 51 to 60 of about 29,800 (242)

Erythema Multiforme Versus Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: Subtle Difference in Presentation, Major Difference in Management.

open access: yesMilitary Medicine, 2020
Erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis are immune-mediated epidermal conditions with variable clinical presentations.
R. Newkirk, D. Fomin, M. Braden
semanticscholar   +1 more source

Diagnosis and management of reactive infectious mucocutaneous eruption

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Medicine's clinical understanding of reactive infectious mucocutaneous eruption (RIME) has evolved over time. It was previously described as Mycoplasma pneumoniae‐induced rash and mucositis (MIRM), and before that as a variant of Stevens‐Johnson Syndrome/Toxic Epidermal Necrolysis. Here, we summarize the current understanding of best practices
Nicole Damari   +2 more
wiley   +1 more source

Important Points in Toxic Epidermal Necrolysis Management

open access: yesOman Medical Journal, 2019
There are several important points that the authors did not highlight which are critical and form the cornerstones in the care of patients with possible TEN.
Sultan
doaj   +1 more source

Cutaneous approach in toxic epidermal necrolysis [PDF]

open access: yesRevista Brasileira de Cirurgia Plástica, 2017
INTRODUCTION: Toxic epidermal necrolysis is a severe acute mucocutaneous condition usually induced by drugs associated with a high rate of morbidity and mortality.
Francisco Carlos Santos Neto   +6 more
doaj   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Toxic Epidermal Necrolysis: Reply [PDF]

open access: yesMedical Journal Armed Forces India, 2007
Dear Editor, The authors wish to thank the reader for the keen interest shown in the article and for his compliments. We would like to clarify the issues raised by him. Toxic Epidermal Necrolysis (TEN) has been reported to develop due to corticosteroids as well as in spite of steroid therapy [1].
N Kumar, NS Walia
openaire   +3 more sources

A Mathematical Model for Allergic Reactions Induced by the Therapy of HIV

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT A new mathematical model for cell evolution in HIV is introduced and studied. Delay differential equations are used to capture the dynamics of immune system cells involved in allergies, as well as the evolution of HIV viruses, infected and uninfected CD4+$$ {}^{+} $$ cells, and cytotoxic T‐lymphocytes, under specific antiretroviral therapy ...
Rawan Abdullah   +3 more
wiley   +1 more source

Toxic Epidermal Necrolysis in an Irradiated Patient Treated with a Nanocrystalline Silver Dressing

open access: yesCase Reports in Dermatology, 2012
Toxic epidermal necrolysis syndrome is a severe exfoliative condition, which may be triggered by anticonvulsant medication. We report a case of toxic epidermal necrolysis syndrome in a 43-year-old female who was receiving radiotherapy for brain ...
Tamara Z. Vern-Gross   +2 more
doaj   +1 more source

A case of toxic epidermal necrolysis associated with apalutamide administration

open access: yes, 2020
Dear Editor, Apalutamide, a novel nonsteroidal antiandrogen agent, is used for the treatment of castration-resistant prostate cancer. Although skin rash is a common side effect of apalutamide, toxic epidermal necrolysis (TEN) has not been reported yet ...
Nobuko Sagawa   +7 more
semanticscholar   +1 more source

Opportunities and Challenges of Population Pharmacogenomics

open access: yesAnnals of Human Genetics, EarlyView.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou   +3 more
wiley   +1 more source

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