Results 131 to 140 of about 546,003 (354)
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Pesquisa Veterinária Brasileira, 2008 Para estudar as intoxicações por plantas que ocorrem na Ilha de Marajó foram visitadas 7 fazendas. Em todas as fazendas visitadas as pastagens eram constituídas de campo nativo, tinham pouco ou nenhuma disponibilidade de forragem e estavam severamente ...
Fábio Py Tortelli +7 more
doaj +1 more source
JUSTIFICATION OF MIXTURE COMPOSITION FOR RECLAMATION OF THE LANDS DISTURBED AS A RESULT OF UNDERGROUND COAL MINING [PDF]
, 2018 Underground coal development is accompanied by significant deformations of the earth's surface, changes in the hydrological mode of groundwater and surface water, as well as other negative consequences.
Pavlychenko, Artem, Tkach, Ilya
core
Some mechanisms involved in the development of iron toxicity symptoms in the rice plant [PDF]
, 1966 Akira Tanaka +2 more
openalex +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source
Possibility of hydrogen sulfide induced iron toxicity of the rice plant [PDF]
, 1968 Akira Tanaka +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun +5 more
wiley +1 more source
Cadmium Toxicity and Tolerance in Plants
, 2019 Of all the non-essential heavy metals, cadmium (Cd) is perhaps the metal which has attracted the most attention in soil science and plant nutrition due to its potential toxicity to humans, and also its relative mobility in the soil-plant system. This review summarizes the toxic symptoms of Cd in plants (i.e.
Shamsul Hayat +4 more
openaire +3 more sources
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
Element concentrations toxic to plants, animals, and man [PDF]
, 1979 L.P. Gough +2 more
openalex +1 more source