Results 181 to 190 of about 2,863,474 (344)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Influence of Heavy Metal Toxicity on Plant Growth, Metabolism and Its Alleviation by Phytoremediation - A Promising Technology

, 2016
Farha Ashfaque, Akhtar Inam, Seema Sahay, Saba Iqbal   +3 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Multi-Task Cascade Forest Framework for Predicting Acute Toxicity across Species. [PDF]

Research (Wash D C)
Liu K, Li R, Wu L, Yang J, Han J, He S, Bo X, Gao J.   +7 more
europepmc   +1 more source

Copper oxide nanoparticles can induce toxicity to the freshwater shredder Allogamus ligonifer

, 2012
Arunava Pradhan, Sahadevan Seena, Cláudia Pascoal, Fernanda Cássio   +3 more
openalex   +2 more sources

Sorafenib and pemetrexed toxicity in cancer cells is mediated via SRC-ERK signaling [PDF]

, 2012
M. Danielle Bareford, Hossein A. Hamed, Jeremy C. Allegood, Nichola Cruickshanks, Andrew Poklepovic, Margaret A. Park, Besim Öğretmen, Sarah Spiegel, Steven Grant, Paul Dent   +9 more
openalex   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Cumulative oesophageal dose and risk of high-grade toxicity in thoracic re-irradiation: a dose/toxicity analysis. [PDF]

Clin Transl Radiat Oncol
Rulach R, Harrow S, J Chalmers A, Fenwick J.   +3 more
europepmc   +1 more source

Glucose catabolism in African trypanosomes. Evidence that the terminal step is catalyzed by a pyruvate transporter capable of facilitating uptake of toxic analogs.

, 1993
John P. Barnard, Baltazar Reynafarje, Peter L. Pedersen   +2 more
openalex   +1 more source

Toxic Effect of Herbicide 2,4-D on the Earthworm Eutyphoeus waltoni Michaelsen [PDF]

, 2015
Vandana Singh, Keshav Singh
openalex   +1 more source