Results 201 to 210 of about 2,863,474 (344)

Genetic Determinants of Hematopoietic Toxicity Risk in Thai Pediatric Patients Undergoing 6-Mercaptopurine Treatment. [PDF]

Clin Transl Sci
Khaeso K, Chainansamit SO, Kuwatjanakul P, Komvilaisak P, Nakkam N, Suwannaying K, Vannaprasaht S, Dornsena A, Tassaneeyakul W.   +8 more
europepmc   +1 more source

Hybrid molecules synergistically mitigate ferroptosis and amyloid-associated toxicities in Alzheimer's disease

Dikshaa Padhi, Prayasee Baruah, Madhu Ramesh, Hariharan Moorthy, Thimmaiah Govindaraju   +4 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Opioid dispensing prior to opioid toxicity hospitalizations and emergency department visits in Canada, 2018-2022. [PDF]

PLoS One
Hamzat B, Cheung G, Eurich DT, Kaboré JL, de Léséleuc L, Liu Z, McCormack D, Missaoui H, Randall JR, Shearer D, Stock D, Gomes T.   +11 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Antiseizure Effects of Cannabidiol in Combination With Cannabigerol in the Maximal Electroshock Seizure Model. [PDF]

Basic Clin Pharmacol Toxicol
Zhou HZ, Scott BW, Oleksak YI, Burnham WM.   +3 more
europepmc   +1 more source

Difference in toxicity reporting between patients and clinicians during systemic chemotherapy in patients with urothelial carcinoma [PDF]

, 2017
Ken Fukushi, Takuma Narita, Shingo Hatakeyama, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Chikara Οhyama   +9 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Author Correction: Humidifier disinfectant, sodium dichloroisocyanurate (NaDCC): assessment of respiratory effects to protect workers’ health

Scientific Reports
DongSeok Seo, Yong-Hoon Lee, JiMin Jo
doaj   +1 more source

Prediction of primary human targets and toxicity mechanisms of imidacloprid using integrative <i>In Silico</i> approaches. [PDF]

Toxicol Rep
Boonyong C, Powthong P.
europepmc   +1 more source