Results 101 to 110 of about 18,256 (198)

Prioritising research on endocrine disruption in the marine environment: a global perspective

Biological Reviews, Volume 101, Issue 2, Page 848-868, April 2026.
ABSTRACT A healthy ocean is a crucial life support system that regulates the global climate, is a source of oxygen and supports major economic activities. A vast and understudied biodiversity from micro‐ to macro‐organisms is integral to ocean health.
Patricia I. S. Pinto, Angelica Miglioli, Carlie A. LaLone, Lisa Baumann, Alice Baynes, Mélanie Blanc‐Legendre, Ibon Cancio, Xavier Cousin, ZhiChao Dang, Rémi Dumollard, Alex T. Ford, Christopher Green, Taisen Iguchi, Philippa Kearney, Thomas Knigge, Christophe Minier, Tiphaine Monsinjon, Marta S. Monteiro, Joachim Sturve, Haruna Watanabe, Hiroshi Yamamoto, Gerald Ankley, Deborah M. Power, Ioanna Katsiadaki   +23 more
wiley   +1 more source

Importance of Toxicokinetics to Assess the Utility of Zebrafish Larvae as Model for Psychoactive Drug Screening Using Meta-Chlorophenylpiperazine (mCPP) as Example

Frontiers in Pharmacology, 2018
The number of new psychoactive substances (NPS) increases rapidly, harming society and fuelling the need for alternative testing strategies. These should allow the ever-increasing number of drugs to be tested more effectively for their toxicity and ...
Krishna Tulasi Kirla, Krishna Tulasi Kirla, Ksenia J. Groh, Ksenia J. Groh, Michael Poetzsch, Rakesh Kumar Banote, Julita Stadnicka-Michalak, Julita Stadnicka-Michalak, Rik I. L. Eggen, Rik I. L. Eggen, Kristin Schirmer, Kristin Schirmer, Kristin Schirmer, Thomas Kraemer   +13 more
doaj   +1 more source

Effects of Chronic Waterborne Nickle Exposure on Two Successive Generations of \u3cem\u3eDaphnia Magna\u3c/em\u3e [PDF]

, 2004
In a 21-d chronic toxicity test in which an F0 generation of Daphnia magna were exposed to waterborne Ni, the noobservable-effect concentration (for survival, reproduction, and growth) was 42 μg Ni L-1, or 58% of the measured 21-d median lethal ...
McGeer, James C., Pane, Eric F., Wood, Chris M.   +2 more
core   +1 more source

Biomarkers for exposure as a tool for efficacy testing of a mycotoxin detoxifier in broiler chickens and pigs [PDF]

, 2019
Applying post-harvest control measures such as adding mycotoxin detoxifying agents is a frequently-used mitigation strategy for mycotoxins. EFSA states that the efficacy of these detoxifiers needs to be tested using specific biomarkers for exposure ...
Croubels, Siska, Devreese, Mathias, Gougoulias, Christos, Lauwers, Marianne, Letor, Ben   +4 more
core   +2 more sources

Contact Allergy to Ingredients of Hair Cosmetics Associated with Occupational and Non‐Occupational Exposure—Trends from 1995 to 2020 in Central Europe, with or without Regulation

Contact Dermatitis, Volume 94, Issue 4, Page 347-363, April 2026.
Among 2678 female hairdressers and 6244 female consumers with contact dermatitis suspected to be related to use of hair cosmetics, including dyes, patch tested in the IVDK between 1995 and 2020, diverging contact allergy trends were observed. In the case of toluene‐2,5‐diamine (PTD) shown in the figure, sensitization was at a stable, high level in ...
Wolfgang Uter, Jakob Ferløv Baselius Schwensen, Brunhilde Blömeke, Olaf Gefeller, Swen M. John, Cara Bieck, Steffen Schubert   +6 more
wiley   +1 more source

Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the developing male Wistar(Han) rat II: chronic dosing causes developmental delay [PDF]

, 2007
We have investigated whether fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat, using chronically exposed rats to ensure continuous exposure of the fetus. 5-6 week old rats were exposed
Bell, David Robert, Clode, Sally, Fan, MingQi, Fernandes, Alwyn, Foster, Paul M D, Jiang, tao, Loizou, George, MacNicoll, Alan, Miller, Brian G, Rose, Martin, Tran, Lang, White, Shaun   +11 more
core   +1 more source

Development of a biomarker for penconazole: a human oral dosing study and a survey of UK residents’ exposure [PDF]

, 2016
Penconazole is a widely used fungicide in the UK; however, to date, there have been no peer-reviewed publications reporting human metabolism, excretion or biological monitoring data.
Cherrie, John W., Cocker, John, Galea, Karen, Jones, Kate, MacCalman, Laura, Sams, Craig, Teedon, Paul, van Tongeren, Martie   +7 more
core   +2 more sources

A Systematic Review of the Toxicokinetics of Micro- and Nanoplastics in Mammals Following Digestive Exposure

Applied Sciences
The high production of plastic, along with its biostability and poorly managed recycling, has led to its widespread presence in the environment. Pollution from microplastics (particles smaller than 5 mm) and nanoplastics (particles smaller than 1 μm ...
Raluca Paula Popa, Alexandru Flaviu Tabaran   +1 more
doaj   +1 more source

Therapeutic drug monitoring of methotrexate after its administration in high doses for osteosarcoma treatment in children

Фармакокинетика и Фармакодинамика, 2020
In children oncology high doses of methotrexate (HD Mtx) use for treatment of osteosarcoma, acute lymphoblastic leukemia and many others tumors. Due to high intra- and interindividual Mtx pharmacokinetic variability it is essential perform monitoring its
A. M. Strizhevskaya, E. G. Golovnya, I. S. Kuleshova, A. Z. Dzampaeva, V. N. Baykova   +4 more
doaj  

A geometric characterization of c-optimal designs for heteroscedastic regression [PDF]

We consider the common nonlinear regression model where the variance as well as the mean is a parametric function of the explanatory variables. The c-optimal design problem is investigated in the case when the parameters of both the mean and the variance
Dette, Holger, Holland-Letz, Tim
core