Results 61 to 70 of about 9,004 (219)
Journal of Applied Toxicology, EarlyView.ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye +3 more
wiley +1 more source
Toxicokinetics parameters for PTB in plasma after oral administration of different doses of PTA.
, 2019 Toxicokinetics parameters for PTB in plasma after oral administration of different doses of PTA.
Godelind Alma Wolf-Jäckel (6866411) +5 more
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Parabens (parahydroxybenzoates), which are frequently used as preservatives in pharmaceuticals, foodstuffs, and personal care products, have recently attracted considerable attention due to their adverse health effects and endocrine‐disrupting properties.
Jung‐Wei Chang +5 more
wiley +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Influence of Female Sex Hormones on GHB Toxicokinetics and Regulation of MCTs and SMCTs
, 2023 Gamma-hydroxybutyric acid (GHB) is an endogenous shorty chain fatty acid that is used clinically as Xyrem to treat narcolepsy. GHB is best known for its illicit use and abuse due to its sedative/hypnotic and euphoric effects. It is used in body building,
Wei, Hao
core +1 more source
Toxicokinetics of Chlorfenapyr and Its Metabolites in Rats
Fayixue ZazhiObjectiveTo establish a chromatography-tandem mass spectrometry method for detecting chlorfenapyr and its metabolite tralopyril in blood, and to investigate the toxicokinetics in rats.MethodsChlorfenapyr （8 mg/kg） was administered orally to rats, and ...
LI Wen-yan +8 more
doaj +1 more source
Toxins, 2016 Bacillus cereus is an opportunistic foodborne agent causing food poisoning and many infectious diseases. The heat-stable emetic toxin cereulide is one of the most prevalent toxins produced by pathogenic B. cereus, resulting in symptoms such as emesis and
Yifang Cui +5 more
doaj +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Titanium dioxide (TiO2), used as a food additive (labeled E171 in Europe), was withdrawn from the European market in 2022. The E171 toxicity mechanism involves its uptake, oxidative stress, DNA damage, and inflammation. It has been hypothesized that the TiO2 accumulation nanoparticles (NPs) or E171 triggers tissue damage, and some studies have
Carmen Ximena Martínez‐Escutia +3 more
wiley +1 more source
httk: R Package for High-Throughput Toxicokinetics
, 2017 Thousands of chemicals have been profiled by high-throughput screening programs such as ToxCast and Tox21; these chemicals are tested in part because most of them have limited or no data on hazard, exposure, or toxicokinetics. Toxicokinetic models aid in
John F. Wambaugh +9 more
core +1 more source
VaccinesBackground/Objectives: Poorly soluble aluminium (Al) compounds have successfully been used for decades as adjuvants in vaccines, enabling an effective immune response.
Karin Weisser +4 more
doaj +1 more source