Results 71 to 80 of about 9,004 (219)
Environmental Toxicology, EarlyView.ABSTRACT Metal contamination in aquatic ecosystems poses substantial risks to freshwater organisms, with mixture effects often deviating from predictions based on single‐metal toxicity. Understanding how age‐specific sensitivities and multiple exposure pathways influence mixture effects is critical for accurate risk assessment.
Sanah Majid +3 more
wiley +1 more source
Maternal Lead Exposure Induces Glandular Alterations in the Salivary Glands of Rat Male Offspring
Environmental Toxicology, EarlyView.ABSTRACT Lead (Pb) is a widely distributed environmental pollutant that is highly noxious due to its toxicokinetic characteristics. Pb exposure can damage vital organ systems, including the central nervous and stomatognathic systems. As salivary glands play an important role in oral homeostasis, this study aimed to investigate the effects of maternal ...
Rayssa Maitê Farias Nazário +8 more
wiley +1 more source
Oral and Intravenous Fumonisin Exposure in Pigs—A Single-Dose Treatment Experiment Evaluating Toxicokinetics and Detoxification [PDF]
, 2018 We examined the toxicokinetics of fumonisin B1 (FB1) and its main metabolites after single dose application intravenously (iv) of 139 nmol FB1 or hydrolyzed FB1 (HFB1)/kg bodyweight (BW) in barrows (BW: 34.4 kg ± 2.7 kg), as well as the toxicokinetics of
Dian Schatzmayr +17 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr +10 more
wiley +1 more source
Comparison of the toxicokinetics of daidzein and bisphenol A in pregnant and non-pregnant DA/Han rats [PDF]
Potentially adverse human and environmental effects due to hormone mimicry of environmental estrogens are a matter of current concern. Environmental estrogens belong to the socalled endocrine active compounds (EAC) and may alter signalling processes of ...
Degen, Gisela H., Selinski, Silvia
core
Toxicokinetics of Chromium in Enchytraeus crypticus (Oligochaeta)
, 2022 Chromium is naturally occurring, but emission from anthropogenic sources can lead to increased soil concentrations. Information on its toxicokinetics is essential in order to understand the time needed to reach toxicity and the mechanisms of uptake ...
Amorim, Mónica J.B. +8 more
core +1 more source
Journal of XenobioticsChemical release incidents in the United States involve hazardous chemicals that can harm nearby communities. A historical tracking of these chemical release incidents from 1991 to 2014 across up to 16 states has been conducted by The Agency for Toxic ...
Sydney Boone +6 more
doaj +1 more source
Advances in organic UV filters for sunscreens over the past decade
Photochemistry and Photobiology, EarlyView.Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon +4 more
wiley +1 more source
Safety and tolerability of amustaline/glutathione pathogen‐reduced red blood cells in neonatal rats
Transfusion, EarlyView.Abstract Background Amustaline (S‐303)/glutathione (GSH) pathogen‐reduced red blood cells (PR‐RBCs) are in development for all adult and pediatric RBC transfusion indications, including neonates and infants. A neonatal rat model evaluated the safety and tolerability of PR‐RBCs during growth and maturation. Study Design and Methods Repeated transfusions
Anne North +3 more
wiley +1 more source