Results 11 to 20 of about 258,157 (266)

Telephonic Medical Toxicology Service in a Low-Resource Setting: Setup, Challenges, and Opportunities

Western Journal of Emergency Medicine, 2020
Poisoning and envenomation are a global health problem for which the mortality burden is shouldered heavily by middle- and low-income countries that often lack poison prevention programs and medical toxicology expertise.
Eveline Hitti, Tharwat El Zahran, Hani Hamade, Brent W. Morgan, Ziad Kazzi   +4 more
doaj   +1 more source

Pioneer women in the development of toxicology in Brazil [PDF]

Brazilian Journal of Medical and Biological Research
Women have always played an important role in the development of toxicology all over the world. Specifically in Brazil, toxicology has had greater female representation than other countries, but women's participation at high hierarchical levels is low ...
L. Melo, T.S. Melo
doaj   +2 more sources

Current advances on the phytochemical composition, pharmacologic effects, toxicology, and product development of Phyllanthi Fructus

Frontiers in Pharmacology, 2022
Phyllanthi Fructus (PF), the edible fruits of Phyllanthus emblica L., serves as an important resource for some health products, foods and drugs due to its high safety and sufficient nutritional value.
Xiaoyu Yan, Qiuju Li, Qiuju Li, Lin Jing, Shuangyue Wu, Wei Duan, Yan Chen, Yan Chen, Dayi Chen, Xiaoqi Pan, Xiaoqi Pan   +10 more
doaj   +1 more source

Nephroprotective Effect of L-Carvone on a Mouse Model of LPS-Induced Sepsis-Associated Renal Injury via Regulation of TLR4/NF-κB/AP-1/IRF-3 and Nrf2/iNOS Molecular Signaling Cascades

Journal of Taibah University Medical Sciences
الملخص: أهداف البحث: يُعد الإنتان من الحالات السريرية الخطيرة الناتجة عن استجابة مناعية غير منضبطة، تؤدي إلى التهاب جهازي واسع النطاق وإصابة متعددة للأعضاء، وتُعد الكلى من أكثر الأعضاء تأثرًا.
Saja M. Shareef, PhD (Pharmacology and Toxicology), Sarmed H. Kathem, PhD (Pharmacology and Toxicology), Hayder Ridha-Salman, PhD (Pharmacology)   +2 more
doaj   +1 more source

Simultaneous Measurement and Distribution Analysis of Urinary Nicotine, Cotinine, Trans-3′-Hydroxycotinine, Nornicotine, Anabasine, and Total Nicotine Equivalents in a Large Korean Population

Molecules, 2023
Measurement of multiple nicotine metabolites and total nicotine equivalents (TNE) might be a more reliable strategy for tobacco exposure verification than measuring single urinary cotinine alone.
Hyun-Seung Lee, Mi-Ryung Chun, Soo-Youn Lee   +2 more
doaj   +1 more source

Proteomics for systems toxicology

Computational and Structural Biotechnology Journal, 2014
Current toxicology studies frequently lack measurements at molecular resolution to enable a more mechanism-based and predictive toxicological assessment.
Bjoern Titz, Ashraf Elamin, Florian Martin, Thomas Schneider, Sophie Dijon, Nikolai V. Ivanov, Julia Hoeng, Manuel C. Peitsch   +7 more
doaj   +1 more source

Network toxicology and its application in studying exogenous chemical toxicity

环境与职业医学
With the continuous development of society, a large number of new chemicals are continuously emerging, which presents a challenge to current risk assessment and safety management of chemicals.
Yanli LIN, Zehua TAO, Zhao XIAO, Chenxu HU, Bobo YANG, Ya WANG, Rongzhu LU   +6 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A Comparative Analysis of Toxicology and Non-Toxicology Care in Intoxicated Patients with Acute Kidney Injury

Medicina
Background and Objectives: Intoxicated patients with acute kidney injury (AKI) experience high morbidity and mortality. While prior studies suggest that toxicology care settings improve outcomes, the impact of care settings on patients with AKI remains ...
Chi-Syuan Pan, Chun-Hung Chen, Wei-Kung Chen, Han-Wei Mu, Kai-Wei Yang, Jiun-Hao Yu   +5 more
doaj   +1 more source

Assessing the scientific research productivity of a leading toxicology journal: A case study of from 2003 to 2012

SAGE Open Medicine, 2014
Background: Bibliometric studies are increasingly being used for research assessments. Bibliometric indicators involve the application of statistical methods to scientific publications to obtain the bibliographics for each journal.
Sa’ed H Zyoud, Samah W Al-Jabi, Waleed M Sweileh, Rahmat Awang   +3 more
doaj   +1 more source