Results 41 to 50 of about 703,561 (360)

A Multi-Level Analysis of World Scientific Output in Pharmacology [PDF]

, 2012
The purpose of this chapter is to analyse international research in “pharmacology, toxicology and pharmaceutics” (hereafter pharmacology) on the basis of the scientific papers listed in the Scopus multidisciplinary database.
Olmeda-Gómez, Carlos, Ovalle-Perandones, María-Antonia, Perianes-Rodríguez, Antonio   +2 more
core  

Insulin-like growth factor binding protein-5 as a biomarker for detection of early liver disease [PDF]

, 2011
Study identifying an Insulin-like growth factor binding protein-5 as a biomarker for detection of early liver disease presented at the annual congress of the british toxicology ...
Anne Pryde, David J. Flint, Emma M. Large, Filippi, John N. Plevris, M. Helen Grant, Nakamura, Sokolovic, Yasuoka, Yasuoka   +9 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

A Comparative Analysis of Toxicology and Non-Toxicology Care in Intoxicated Patients with Acute Kidney Injury

Medicina
Background and Objectives: Intoxicated patients with acute kidney injury (AKI) experience high morbidity and mortality. While prior studies suggest that toxicology care settings improve outcomes, the impact of care settings on patients with AKI remains ...
Chi-Syuan Pan, Chun-Hung Chen, Wei-Kung Chen, Han-Wei Mu, Kai-Wei Yang, Jiun-Hao Yu   +5 more
doaj   +1 more source

In Vitro, Oral Acute, and Repeated 28-Day Oral Dose Toxicity of a Mixed-Valence Polyoxovanadate Cluster

Pharmaceuticals, 2023
Polyoxovanadates (POV) are a subgroup of polyoxometalates (POM), which are nanosized clusters with reported biological activities. This manuscript describes the first toxicity evaluation of a mixed-valence polyoxovanadate, pentadecavanadate, (Me4N)6 ...
Mariana de M. Barbosa, Lidiane M. A. de Lima, Widarlane A. da S. Alves, Eucilene K. B. de Lima, Luzia A. da Silva, Thiago D. da Silva, Kahoana Postal, Mohammad Ramadan, Kateryna Kostenkova, Dayane A. Gomes, Giovana G. Nunes, Michelly C. Pereira, Wagner E. da Silva, Mônica F. Belian, Debbie C. Crans, Eduardo C. Lira   +15 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Arab Scientific Working Group for Forensic Toxicology (ASWGFT): Guidelines for Method Validation in Forensic Toxicology

Arab Journal of Forensic Sciences & Forensic Medicine, 2017
Reliable results and valid analytical data are an essential requirement for proper interpretation of forensic toxicology cases, especially when evaluating scientific studies and daily routine work, and when presenting any toxicological findings as ...
Abdulsallam A. Bakdash, Jihad Al-Qudsi, Huda M. Hassan   +2 more
doaj   +1 more source

Parthenin—A Sesquiterpene Lactone with Multifaceted Biological Activities: Insights and Prospects

Molecules, 2021
Parthenin, a sesquiterpene lactone of pseudoguaianolide type, is the representative secondary metabolite of the tropical weed Parthenium hysterophorus (Asteraceae).
Amarpreet Kaur, Shalinder Kaur, Rupali Jandrotia, Harminder Pal Singh, Daizy Rani Batish, Ravinder Kumar Kohli, Virendra Singh Rana, Najam A. Shakil   +7 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The Concentration of Selected Heavy Metals in Muscles, Liver and Kidneys of Pigs Fed Standard Diets and Diets Containing 60% of New Rye Varieties

Animals, 2021
The carry-over of heavy metals from feed to muscles is generally low if animals are fed with a standard diet containing amounts below the maximum permissible levels.
Agnieszka Chałabis-Mazurek, Jose Luis Valverde Piedra, Siemowit Muszyński, Ewa Tomaszewska, Sylwia Szymańczyk, Sylwester Kowalik, Marcin B. Arciszewski, Anna Zacharko-Siembida, Tomasz Schwarz   +8 more
doaj   +1 more source