Results 51 to 60 of about 839,197 (349)

A Comparative Analysis of Toxicology and Non-Toxicology Care in Intoxicated Patients with Acute Kidney Injury

open access: yesMedicina
Background and Objectives: Intoxicated patients with acute kidney injury (AKI) experience high morbidity and mortality. While prior studies suggest that toxicology care settings improve outcomes, the impact of care settings on patients with AKI remains ...
Chi-Syuan Pan   +5 more
doaj   +1 more source

Arab Scientific Working Group for Forensic Toxicology (ASWGFT): Guidelines for Method Validation in Forensic Toxicology

open access: yesArab Journal of Forensic Sciences & Forensic Medicine, 2017
Reliable results and valid analytical data are an essential requirement for proper interpretation of forensic toxicology cases, especially when evaluating scientific studies and daily routine work, and when presenting any toxicological findings as ...
Abdulsallam A. Bakdash   +2 more
doaj   +1 more source

A new occupational and environmental hazard – nanoplastic

open access: yesMedycyna Pracy, 2020
Problems arising from the accumulation of plastic waste in the environment have become global. Appeals to stop the usage of disposable drinking straws or plastic cutlery did not come out without reason – 320 million tons of plastic products are produced ...
Michał Rakowski, Agnieszka Grzelak
doaj   +1 more source

Botulinum Neurotoxins (BoNTs) and Their Biological, Pharmacological, and Toxicological Issues: A Scoping Review

open access: yesApplied Sciences, 2021
Botulinum toxins or neurotoxins (BoNTs) are the most potent neurotoxins known, and are currently extensively studied, not only for their potential lethality, but also for their possible therapeutic and cosmetic uses.
Massimo Corsalini   +10 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

In Vitro, Oral Acute, and Repeated 28-Day Oral Dose Toxicity of a Mixed-Valence Polyoxovanadate Cluster

open access: yesPharmaceuticals, 2023
Polyoxovanadates (POV) are a subgroup of polyoxometalates (POM), which are nanosized clusters with reported biological activities. This manuscript describes the first toxicity evaluation of a mixed-valence polyoxovanadate, pentadecavanadate, (Me4N)6 ...
Mariana de M. Barbosa   +15 more
doaj   +1 more source

ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology.

open access: yesChemical Research in Toxicology, 2016
The U.S. Environmental Protection Agency's (EPA) ToxCast program is testing a large library of Agency-relevant chemicals using in vitro high-throughput screening (HTS) approaches to support the development of improved toxicity prediction models. Launched
A. Richard   +17 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Parthenin—A Sesquiterpene Lactone with Multifaceted Biological Activities: Insights and Prospects

open access: yesMolecules, 2021
Parthenin, a sesquiterpene lactone of pseudoguaianolide type, is the representative secondary metabolite of the tropical weed Parthenium hysterophorus (Asteraceae).
Amarpreet Kaur   +7 more
doaj   +1 more source

Insulin-like growth factor binding protein-5 as a biomarker for detection of early liver disease [PDF]

open access: yes, 2011
Study identifying an Insulin-like growth factor binding protein-5 as a biomarker for detection of early liver disease presented at the annual congress of the british toxicology ...
Anne Pryde   +9 more
core   +1 more source

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