Results 71 to 80 of about 277,535 (215)

Investigation of a foodborne disease outbreak caused by Clostridium perfringens in Guizhou Province and pathogen tracing

Zhongguo shipin weisheng zazhi
ObjectiveEpidemiological investigation of a foodborne disease outbreak triggered by Clostridium perfringens in a school in Guiyang， traceability analysis of etiologic foods and pathogens， and exploration of the application of the new technology of whole ...
ZHANG Li, DAI Hua, JIAN Jie, HUANG Jingyu, JIANG Jiajun, ZHOU Yajuan, TIAN Jigui, ZHU Shu, LIAO Chun, LI Jun, LI Weiwei, GUO Hua   +11 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Shiga Toxin: Expression, Distribution, and Its Role in the Environment

Toxins, 2011
In this review, we highlight recent work that has increased our understanding of the production and distribution of Shiga toxin in the environment. Specifically, we review studies that offer an expanded view of environmental reservoirs for Shiga toxin ...
Steven A. Mauro, Gerald B. Koudelka
doaj   +1 more source

A Multi-Layer-Controlled Strategy for Cloning and Expression of Toxin Genes in Escherichia coli. [PDF]

Toxins (Basel), 2023
Vandierendonck J, Girardin Y, De Bruyn P, De Greve H, Loris R.   +4 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Unusual accelerated rate of deletions and insertions in toxin genes in the venom glands of the pygmy copperhead (Austrelaps labialis) from kangaroo island

BMC Evolutionary Biology, 2008
Background Toxin profiling helps in cataloguing the toxin present in the venom as well as in searching for novel toxins. The former helps in understanding potential pharmacological profile of the venom and evolution of toxins, while the latter ...
Kini R Manjunatha, Reza Md Abu, Tram Nguyen, Doley Robin   +3 more
doaj   +1 more source

Profiling toxin genes and antibiotic resistance in Bacillus cereus isolated from pre-launch spacecraft. [PDF]

Front Microbiol, 2023
Mohammadi B, Gorkina N, Pérez-Reyes ME, Smith SA.   +3 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Six New Genes Required for Production of T-Toxin, a Polyketide Determinant of High Virulence of Cochliobolus heterostrophus to Maize

Molecular Plant-Microbe Interactions, 2010
Southern Corn Leaf Blight, one of the worst plant disease epidemics in modern history, was caused by Cochliobolus heterostrophus race T, which produces T-toxin, a determinant of high virulence to maize carrying Texas male sterile cytoplasm.
Patrik Inderbitzin, Thipa Asvarak, B. Gillian Turgeon   +2 more
doaj   +1 more source

Evolution of Three-Finger Toxin Genes in Neotropical Colubrine Snakes (Colubridae). [PDF]

Toxins (Basel), 2023
Srodawa K, Cerda PA, Davis Rabosky AR, Crowe-Riddell JM.   +3 more
europepmc   +1 more source