Results 101 to 110 of about 958,820 (304)

Comparative evaluation of chromium methionine chelate and Nano chromium in alleviating Zearalenone-Induced oxidative stress

Current Research in Biotechnology
Zearalenone, a mycotoxin from Fusarium fungi found in contaminated feed, poses toxicity risks to livestock. The administration of antioxidant compounds has emerged as a potential approach for mitigating zearalenone-induced toxicity.
Mohammad Alizadeh, Arash Abolhassani, Amirhosein Zanjani Tabasi, Golnoush Shirkhani, Asal Ghahreman, Negin Shafaei, Ehsan Oskoueian, Ehsan Karimi   +7 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Toxin-antitoxin cassettes identified by TA finder in investigated Salmonella strains with functional classification of candidate toxin and antitoxin proteins.

, 2021
Toxin-antitoxin cassettes identified by TA finder in investigated Salmonella strains with functional classification of candidate toxin and antitoxin proteins.
Taruna Anand (828898), Rajesh Kumar Vaid (11302529), Bhupendra Nath Tripathi (9032255), Zoozeal Thakur (11302532), Sanjay Kumar (8853)   +4 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Molecular analysis of mammalian adenylyl cyclases and bacterial adenylyl cyclase toxins [PDF]

, 2009
The cAMP signaling pathway is crucial for many physiological processes and many disease states like neurodegenerative diseases, mood disorders, pain, drug dependency or heart failure.
Göttle, Martin
core   +1 more source

Clostridium perfringens Alpha-Toxin Induces Gm1a Clustering and Trka Phosphorylation in the Host Cell Membrane.

PLoS ONE, 2015
Clostridium perfringens alpha-toxin elicits various immune responses such as the release of cytokines, chemokines, and superoxide via the GM1a/TrkA complex.
Teruhisa Takagishi, Masataka Oda, Michiko Kabura, Mie Kurosawa, Kaori Tominaga, Shiori Urano, Yoshibumi Ueda, Keiko Kobayashi, Toshihide Kobayashi, Jun Sakurai, Yutaka Terao, Masahiro Nagahama   +11 more
doaj   +1 more source

Snake venom toxin from vipera lebetina turanica induces apoptosis of colon cancer cells via upregulation of ROS- and JNK-mediated death receptor expression

BMC Cancer, 2012
Background Abundant research suggested that the cancer cells avoid destruction by the immune system through down-regulation or mutation of death receptors.
Park Mi, Jo MiRan, Won Dohee, Song Ho, Han Sang, Song Min, Hong Jin   +6 more
doaj   +1 more source

Inhibitors of synaptic vesicle exocytosis reduce surface expression of postsynaptic glutamate receptors

Animal Cells and Systems, 2020
Bafilomycin A1, a vacuolar H+-ATPase inhibitor, and botulinum toxin B and tetanus toxin, both vesicle fusion inhibitors, are widely known exocytosis blockers that have been used to inhibit the presynaptic release of neurotransmitters.
Dong Ho Woo, Young-Na Hur, Minwoo Wendy Jang, C. Justin Lee, Mikyoung Park   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Botulinum Toxin as Preventive Treatment for Migraine: A Randomized Double-Blind Study [PDF]

, 2009
Aim: To determine if botulinum toxin type A (BoNT-A) injections can reduce the frequency and severity of migraines. Methods: Patients (n = 127) were randomized to receive placebo or two doses of BoNT-A (Dysport (R)). The primary endpoint was reduction in
Toelle, Thomas, Straube, Andreas, Ceballos-Baumann, Andres, Volker Pfaffenrath, Petri, Susanne, Pfaffenrath, Volker, Susanne Petri, Thomas Tölle, Ulrich Stefenelli, Andres Ceballos-Baumann, Stefenelli, Ulrich, Andreas Straube, Petri, S;Tölle, T;Straube, A;Pfaffenrath, V;Stefenelli, U;Ceballos-Baumann, A, Petri, Susanne;Tölle, Thomas;Straube, Andreas;Pfaffenrath, Volker;Stefenelli, Ulrich;Ceballos-Baumann, Andres   +13 more
core   +1 more source