Results 191 to 200 of about 595,436 (374)

BioTD: an online database of biotoxins [PDF]

arXiv
Biotoxins, mainly produced by venomous animals, plants and microorganisms, exhibit high physiological activity and unique effects such as lowering blood pressure and analgesia. A number of venom-derived drugs are already available on the market, with many more candidates currently undergoing clinical and laboratory studies.
arxiv  

Development and validation of a LC-MS method for the quantification of microcystins in fish for their monitoring in environmental and food context

Journal of Agriculture and Food Research
Cyanobacterial blooms in aquatic ecosystems can result in the accumulation of cyanotoxins in other organisms. Fish can potentially accumulate large amounts of cyanotoxins through their direct interaction with contaminated water and the ingestion of ...
Camille Van Camp, Wannes Hugo R. Van Hassel, Jeroen Van Wichelen, Julien Masquelier   +3 more
doaj  

Evaluation of adhesin genes and risk factors associated with urinary tract infections by drug-resistant uropathogenic Escherichia coli in North of Iran

Journal of Infection in Developing Countries
Background: Uropathogenic Escherichia coli (UPEC) isolates, have a wide variety of virulence factors to promote colonization and survival in the urinary tract.
Raheleh Sheikhi, Mohammad Esmaeil Amini, Leila Alidoust, Zahra Atrkar Roushan, Iraj Nikokar   +4 more
doaj   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Can Large Language Models Design Biological Weapons? Evaluating Moremi Bio [PDF]

arXiv
Advances in AI, particularly LLMs, have dramatically shortened drug discovery cycles by up to 40% and improved molecular target identification. However, these innovations also raise dual-use concerns by enabling the design of toxic compounds. Prompting Moremi Bio Agent without the safety guardrails to specifically design novel toxic substances, our ...
arxiv  

Bradycardia of central origin produced by injections of tetanus toxin into the vagus nerve

, 1949
N Ambache, O. C. J. Lippold
openalex   +2 more sources

Studies of the Properties of Bouillon Filtrates of the Meningococcus: Production of a Soluble Toxin [PDF]

, 1931
N. S. Ferry, John F. Norton, Angharad Steele   +2 more
openalex   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

THE DICK TEST AND ACTIVE IMMUNIZATION WITH SCARLET FEVER STREPTOCOCCUS TOXIN

, 1924
Abraham Zingher
openalex   +2 more sources

THE TREATMENT OF INOPERABLE MALIGNANT TUMORS WITH THE TOXINS OF ERYSIPELAS AND BACILLUS PRODIGIOSUS [PDF]

, 1895
NULL AUTHOR_ID
openalex   +1 more source