Results 191 to 200 of about 919,409 (398)

Structural and functional analysis of Hydra Actinoporin-Like Toxin 1 (HALT-1) [PDF]

, 2021
De‐Sheng Ker, Hong Xi Sha, Mohd Anuar Jonet, Jung Shan Hwang, Chyan Leong Ng   +4 more
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Autoregulation of bacterial gene expression: lessons from the MazEF toxin–antitoxin system [PDF]

, 2018
Nela Nikolić
openalex   +1 more source

Standardized algorithm for muscle selection and dosing of botulinum toxin for Parkinson tremor using kinematic analysis [PDF]

, 2020
Olivia Samotus, J. Jack Lee, Mandar Jog
openalex   +1 more source

Can Botulinum Toxin-A Contribute to Reconstructing the Physiological Homeostasis of the Masticatory Complex in Short-Faced Patients during Occlusal Therapy? A Prospective Pilot Study [PDF]

, 2022
Xin Li, Xiaoyan Feng, Juan Li, Xinyu Bao, Jinghong Xu, Jun Lin   +5 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Novel Role for Animal Innate Immune Molecules: Enterotoxic Activity of a Snail Egg MACPF-Toxin [PDF]

, 2020
Matías L. Giglio, Santiago Ituarte, Andrés Ibáñez, Marcos S. Dreon, Eduardo Prieto, Patricia E. Fernández, Horacio Heras   +6 more
openalex   +1 more source

Clostridium botulinum C3 Toxin for Selective Delivery of Cargo into Dendritic Cells and Macrophages [PDF]

, 2022
Maximilian Fellermann, Mia Stemmer, Reiner Noschka, Fanny Wondany, Stephan Fischer, Jens Michaelis, Steffen Stenger, Holger Barth   +7 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Modeling emergence of Wolbachia toxin-antidote protein functions with an evolutionary algorithm [PDF]

, 2023
John F. Beckmann, Joe Gillespie, Daniel R. Tauritz   +2 more
openalex   +1 more source