Results 211 to 220 of about 552,298 (312)

Inter- and Intraspecific Venom Variation in the Reclusive Rear-Fanged Black-Striped Snakes (<i>Coniophanes</i>). [PDF]

Toxins (Basel)
Fowler JH, Rosales-García RA, Rautsaw RM, Hogan MP, Hofmann EP, Mason AJ, Nagesan R, Borja M, Herrera L, Castañeda-Gaytan G, Davis Rabosky AR, Rokyta DR, Parkinson CL.   +12 more
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Mycotoxins and plant diseases in a changing climate: from pathogen ecology to smart surveillance and mitigation strategies. [PDF]

Front Fungal Biol
Dehbi I, Farhaoui A, Benamar K, Smouni FE, Achetoui H, Kouighat M, Janati M, Barka EA, Mazouz H, Lahlali R.   +9 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Skin Irritation-Associated Dinoflagellate <i>Vulcanodinium rugosum</i> Isolated from Cienfuegos Bay, Cuba: Toxin Profile and Cell Growth Characterization Under Laboratory Conditions. [PDF]

Toxins (Basel)
Moreira-Gonzalez AR, Churro C, Marques V, Díaz-Asencio L, Lago DC, Costa PR.   +5 more
europepmc   +1 more source

Children’s Health and Environmental Exposure Risks: Information Gaps, Scientific Uncertainty, and Regulatory Reform [PDF]

, 2007
Blais, Lynn, Wagner, Wendy
core   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Conkazal-M1 from the MKAVA family of conotoxins: A dual-function protease inhibitor and neuroactive peptide. [PDF]

Protein Sci
Hackney CM, Koch TL, Ryding NL, Rogalski A, Chase K, Giglio ML, Espino SS, Acyatan ZG, Watkins M, Olivera BM, Safavi-Hemami H, Teilum K, Ellgaard L.   +12 more
europepmc   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Botulinum Toxin Treatment of Stiff Person Syndrome-A Critical Review and Update. [PDF]

Toxins (Basel)
Tohidian AG, Comtesse SM, Etemadmoghadam S, Jabbari B.   +3 more
europepmc   +1 more source