Results 201 to 210 of about 100,749 (257)
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Toxins: Bacterial and Marine Toxins
Clinics in Laboratory Medicine, 2006The term toxin refers in a specific way to a toxic substance of biologic origin; that is, a true toxin is a poison produced by a living organism. The purpose of this article is to review some of the most potentially dangerous toxins of concern today. Mechanisms of action, routes of exposure, diagnostic tools, and treatment recommendations are addressed.
Matthew, Salzman +2 more
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Hormone, lectin and toxin-toxin conjugates
1988In order to better understand the relative importance of the A and B chains of diphtheria toxin and ricin, chimeras or hybrid toxins have been constructed with diphtheria toxin subunits and ricin subunits coupled to a number of different binding moieties.
T N, Oeltmann, R G, Wiley
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Trends in Microbiology, 2001
Researchers from Harvard Medical School have identified mutants of the anthrax toxin that could be used in the development of a therapeutic vaccine, as reported in Science. Rats injected with mutant protective antigen and a normally lethal dose of the anthrax toxin survived, suggesting that the mutant antigen could be useful as both a vaccine and an ...
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Researchers from Harvard Medical School have identified mutants of the anthrax toxin that could be used in the development of a therapeutic vaccine, as reported in Science. Rats injected with mutant protective antigen and a normally lethal dose of the anthrax toxin survived, suggesting that the mutant antigen could be useful as both a vaccine and an ...
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Current Opinion in Structural Biology, 1995
Crystal structures of shiga and pertussis toxins have recently revealed a remarkable degree of structural homology among the members of the AB5 class of bacterial toxins. Other structures have provided a detailed view of the molecular basis of receptor binding specificity of cholera toxin, and of the heat-labile enterotoxin of Escherichia coli.
E A, Merritt, W G, Hol
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Crystal structures of shiga and pertussis toxins have recently revealed a remarkable degree of structural homology among the members of the AB5 class of bacterial toxins. Other structures have provided a detailed view of the molecular basis of receptor binding specificity of cholera toxin, and of the heat-labile enterotoxin of Escherichia coli.
E A, Merritt, W G, Hol
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Epsilon toxin: a fascinating pore‐forming toxin
The FEBS Journal, 2011Epsilon toxin (ETX) is produced by strains of Clostridium perfringens classified as type B or type D. ETX belongs to the heptameric β‐pore‐forming toxins including aerolysin and Clostridium septicum alpha toxin, which are characterized by the formation of a pore through the plasma membrane of eukaryotic cells consisting in a β‐barrel of 14 amphipatic β
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Molecular Nutrition & Food Research, 2006
AbstractBlue‐green algae are found in lakes, ponds, rivers and brackish waters throughout the world. In case of excessive growth such as bloom formation, these bacteria can produce inherent toxins in quantities causing toxicity in mammals, including humans. These cyanotoxins include cyclic peptides and alkaloids.
Marian E, van Apeldoorn +3 more
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AbstractBlue‐green algae are found in lakes, ponds, rivers and brackish waters throughout the world. In case of excessive growth such as bloom formation, these bacteria can produce inherent toxins in quantities causing toxicity in mammals, including humans. These cyanotoxins include cyclic peptides and alkaloids.
Marian E, van Apeldoorn +3 more
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Toxicon, 2001
Shiga toxin and Shiga-like toxins belong to the group of protein toxins which have a moiety that binds to the cell surface and another enzymatically active moiety that after entry into the cytosol inhibits protein synthesis enzymatically. The toxins can also cause apoptosis by mechanisms that may be different from the effect on the protein synthesis ...
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Shiga toxin and Shiga-like toxins belong to the group of protein toxins which have a moiety that binds to the cell surface and another enzymatically active moiety that after entry into the cytosol inhibits protein synthesis enzymatically. The toxins can also cause apoptosis by mechanisms that may be different from the effect on the protein synthesis ...
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Kidney international. Supplement, 1988
It is the purpose of this paper to review our present knowledge about uremic toxicity, with a special emphasis on the methods that have been used to try to resolve this problem. More and more, sophisticated methods become available for the study of uremic toxicity.
Ringoir, S.M.G. +2 more
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It is the purpose of this paper to review our present knowledge about uremic toxicity, with a special emphasis on the methods that have been used to try to resolve this problem. More and more, sophisticated methods become available for the study of uremic toxicity.
Ringoir, S.M.G. +2 more
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2012
Toxins are produced by numerous microorganisms and invertebrates as well as by higher plants and animals. Venoms are produced by many groups of animals, from coelenterates to vertebrates. While toxins and venoms are the primary toxicological concern in natural ecosystems, they are frequently of importance in agroecosystems and in military deployments ...
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Toxins are produced by numerous microorganisms and invertebrates as well as by higher plants and animals. Venoms are produced by many groups of animals, from coelenterates to vertebrates. While toxins and venoms are the primary toxicological concern in natural ecosystems, they are frequently of importance in agroecosystems and in military deployments ...
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Current Opinion in Gastroenterology, 1999
The application of molecular techniques to the study of bacterial pathogenesis has made possible discoveries that are changing the way scientists view the bacterium-host interaction. Today, research on the molecular basis of the pathogenesis of infective diarrheal diseases of necessity transcends established boundaries between cell biology ...
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The application of molecular techniques to the study of bacterial pathogenesis has made possible discoveries that are changing the way scientists view the bacterium-host interaction. Today, research on the molecular basis of the pathogenesis of infective diarrheal diseases of necessity transcends established boundaries between cell biology ...
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