Results 191 to 200 of about 323,812 (313)

Arresting the Activity of Bacterial β-Barrel Pore-Forming Toxins by Cysteine Insertion Mutagenesis in the Homologous Region. [PDF]

Int J Mol Sci
Siunov AV, Melnik BS, Nagel AS, Andreeva-Kovalevskaya ZI, Rudenko NV, Karatovskaya AP, Vetrova OS, Zamyatina AV, Brovko FA, Solonin AS.   +9 more
europepmc   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

Arthritis Care &Research, EarlyView.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge, Gabriela Schmajuk, Sristi Sharma, Colleen P. Flanagan, Sara Faghihi‐Kashani, Ning Zhang, Mary A. Whooley   +6 more
wiley   +1 more source

Revisiting the hemodiafiltration with endogenous reinfusion: what is its merit in clinical practice? A narrative review. [PDF]

Ann Med
Chen Z, Shao Q, Wang H, Xue C, Yang B, Liu N.   +5 more
europepmc   +1 more source

Mycotoxins and plant toxins in plant-based drinks

Plant-based milk alternatives have gained relevance in recent years due to the growing popularity of a vegan lifestyle, rising health consciousness and environmental concerns.
Lorenz, Nicole, Bahlmann, Arnold, Sarvan, Irmela, Jung, Christian, Hutzler, Christoph, Weigel, Stefan   +5 more
core  

The Gut-Kidney-Metabolic Axis: Impact of Gut-Derived Uremic Toxins on Insulin Resistance in Diabetic Kidney Disease. [PDF]

Int J Mol Sci
Delrue C, Vinckier M, Speeckaert R, Marzocco S, Speeckaert MM.   +4 more
europepmc   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian, Chloe Yue, Steve D Levasseur, Hui Xie, J. Antonio Avina‐Zubieta   +4 more
wiley   +1 more source

<i>Alternaria</i> Mycotoxins in the Hemp (<i>Cannabis sativa</i> L.) Food Chain. [PDF]

Toxins (Basel)
Bertuzzi T, Schiavi L, Siboni F, Battaglia R, Giorni P, Capuccinello DI, Montanari M.   +6 more
europepmc   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

A Review of the Chemical Properties, Mechanisms of Action, and Structure-Activity Relationships of Jellyfish Toxins. [PDF]

Curr Issues Mol Biol
Wang P, Li L, Kong C, Fu Z, Li Y, Chi H.
europepmc   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source