Results 131 to 140 of about 159,524 (313)
PLoS Pathogens, 2016 The immune privileged nature of the CNS can make it vulnerable to chronic and latent infections. Little is known about the effects of lifelong brain infections, and thus inflammation, on the neurological health of the host.
Clement N David +16 more
semanticscholar +1 more source
Ocular sequelae of congenital toxoplasmosis in Brazil compared with Europe [PDF]
, 2008 Toxoplasmic retinochoroiditis appears to be more severe in Brazil, where it is a leading cause of blindness, than in Europe, but direct comparisons are lacking.
Bahia-Oliveira, LM +9 more
core +3 more sources
Toxoplasma gondii Hsp70 as a danger signal in Toxoplasma gondii-infected mice
Cell Stress & Chaperones, 2000 Toxoplasma gondii Hsp70, T gondii Hsp30/bag1, and surface antigen 1 messenger RNAs were shown to be useful in analyzing stage conversion of T gondii between bradyzoites and tachyzoites. The high-level expression of T gondii Hsp70 was correlated with mortality in interferon-gamma knockout mice infected with T gondii.
Yoichi Iwakura +8 more
openaire +4 more sources
Cloning of cDNA Encoding GRA1 Protein of Tachyzoite Toxoplasma Gondii Local Isolate
Indonesian Journal of Biotechnology, 2005 Gene encoding GRA1 protein is potent DNA-vaccine candidate against toxoplasmosis. The aim of the research was to clone the gene encoding GRA1 protein of tachyzoite Toxoplasma gondii local isolate by DNA recombinant technology.
Erma Sulistyaningsih +3 more
doaj +1 more source
Impact of environmental factors on the emergence, transmission and distribution of Toxoplasma gondii
Parasites & Vectors, 2016 Toxoplasma gondii is an obligate intracellular protozoan that poses a great threat to human health and economic well-being worldwide. The effects of environmental factors such as changing climate and human activities on the ecology of this protozoan are ...
Chao Yan +3 more
semanticscholar +1 more source
Two essential light chains regulate the MyoA lever arm to promote Toxoplasma gliding motility [PDF]
, 2015 Key to the virulence of apicomplexan parasites is their ability to move through tissue and to invade and egress from host cells. Apicomplexan motility requires the activity of the glideosome, a multicomponent molecular motor composed of a type XIV myosin,
Alonso, Hernan +8 more
core +2 more sources
Juvenile Dermatomyositis Triggered by Influenza B: A Case Report on Viral‐Induced Autoimmunity
Pediatric Dermatology, EarlyView.ABSTRACT A previously healthy 13‐year‐old boy developed juvenile dermatomyositis (JDM) shortly after a confirmed influenza B infection, presenting with progressive proximal muscle weakness and classic cutaneous findings. Laboratory tests revealed elevated muscle enzymes and myositis‐specific autoantibodies, supporting the diagnosis.
Santiago Dans‐Caballero +4 more
wiley +1 more source
Journal of Experimental Medicine, 2016 Gay et al. identify a Toxoplasma gondii secreted effector that recruits NuRD transcriptional repressor and blocks IFN-γ–stimulated STAT1-dependent gene expression, thus dampening host responses to infection.
Gabrielle Gay +12 more
semanticscholar +1 more source
CD40, autophagy and Toxoplasma gondii [PDF]
Memórias do Instituto Oswaldo Cruz, 2009 Toxoplasma gondii represents a pathogen that survives within host cells by preventing the endosomal-lysosomal compartments from fusing with the parasitophorous vacuoles. The dogma had been that the non-fusogenic nature of these vacuoles is irreversible. Recent studies revealed that this dogma is not correct.
openaire +4 more sources
Risk Analysis, EarlyView.Abstract Hepatitis E virus (HEV) can lead to liver disease in humans. In the Netherlands, the consumption of pig meat is thought to be the main contributor to the total burden of disease caused by HEV. In this study, the number of cases and lost disability‐adjusted‐life‐years (DALYs) due to HEV in pig meat were estimated by simulating HEV through the ...
M. Focker +5 more
wiley +1 more source