Comparative Immunopathology of Toxoplasma gondii Natural Infections in Marmosets (Callithrix spp.) and Howler Monkeys (Alouatta spp.), Brazil [PDF]
Journal of Medical Primatology, Volume 55, Issue 5, October 2026.ABSTRACT Introduction Neotropical primates (NTPs) present varying susceptibility to toxoplasmosis caused by Toxoplasma gondii, but their immunopathogenic responses remain poorly understood. Materials and Methods Local immune responses were characterized in the liver, spleen, and central nervous system (CNS) of 50 naturally infected NTPs (31 Callithrix ...
Marina Pellegrino +9 more
wiley +2 more sources
Rpf‐Toxo: A Preliminary Computationally Designed Dense Granule Antigen‐Based Multi‐Epitope Vaccine Against Toxoplasma gondii [PDF]
Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.This graphical abstract summarizes the in silico design of the multi‐epitope vaccine candidate Rpf‐Toxo (Seq4) against Toxoplasma gondii. The workflow includes antigen selection, epitope mapping, vaccine construction, structural and immunological evaluation, toll‐like receptor‐4 docking, immune simulation, safety assessment, codon optimisation and ...
Mohamad Hosein Safari +7 more
wiley +2 more sources
Current Biology, 2018 Putting cat lovers on notice: Toxoplasma gondii is here to control your brain…or is it? Kochanowsky and Koshy shine the spotlight on this notorious pathogen.
Joshua A, Kochanowsky, Anita A, Koshy
+5 more sources
Vaccines against toxoplasma gondii : challenges and opportunities [PDF]
, 2009 Development of vaccines against Toxoplasma gondii infection in humans is of high priority, given the high burden of disease in some areas of the world like South America, and the lack of effective drugs with few adverse effects.
Jongert, Erik +4 more
core +4 more sources
Maternal inheritance and stage-specific variation of the apicoplast in Toxoplasma gondii during development in the intermediate and definitive host [PDF]
, 2005 The structure and location of Toxoplasma gondii apicoplasts were examined in intermediate and definitive hosts and shown to vary in a stage-specific manner.
Henriquez, F L +7 more
core +4 more sources
Studies on a murine model of congenital toxoplasmosis : vertical disease transmission only occurs in BALB/c mice infected for the first time during pregnancy [PDF]
, 1992 The incidence of congenital toxoplasmosis was determined by an ELISA in the litters of BALB/c mice which had been infected 8 weeks before mating, on day 12 of pregnancy, or on both these occasions.
Roberts, C W +2 more
core +4 more sources
Changing climate-changing pathogens: Toxoplasma gondii in North-Western Europe [PDF]
, 2009 In this review, we describe the effects of global climate change for one specific pathogen: the parasite Toxoplasma gondii. It is postulated that an increase of T.
Meerburg, B.G. +3 more
core +1 more source
The transcriptome of Toxoplasma gondii
BMC Biology, 2005 AbstractBackgroundToxoplasma gondiigives rise to toxoplasmosis, among the most prevalent parasitic diseases of animals and man. Transformation of the tachzyoite stage into the latent bradyzoite-cyst form underlies chronic disease and leads to a lifetime risk of recrudescence in individuals whose immune system becomes compromised.
Roos David S +5 more
openaire +3 more sources
Toxoplasma gondii and Epilepsy
Turkish Journal of Parasitology, 2016 Toxoplasma gondii is a zoonotic parasite can be seen in all the vital organ; in the acute phase, it can be found in the blood, cerebrospinal fluid, semen, tears, saliva, urine, and in almost all body fluids. Transplasental infection can lead to fetal damage and miscarriage.
Erol, Ayaz +2 more
openaire +2 more sources