Virulent and avirulent strains of Toxoplasma gondii which differ in their glycosylphosphatidylinositol content induce similar biological functions in macrophages [PDF]
Glycosylphosphatidylinositols (GPIs) from several protozoan parasites are thought to elicit a detrimental stimulation of the host innate immune system aside their main function to anchor surface proteins.
Ricardo T. Gazzinelli (164680) +43 more
core +2 more sources
Immunological studies of chronic ocular toxoplasmosis : up-regulation of major histocompatibility complex class I and transforming growth factor beta and a protective role for interleukin-6 [PDF]
A murine model was used to characterize the local immune and inflammatory response during ocular toxoplasmosis. Major histocompatibility complex (MHC) class I, normally expressed at low levels in immune-privileged sites such as the eye, was up-regulated ...
Byrne, N. +6 more
core +4 more sources
Anti‐Glykan‐Antikörper spielen sowohl bei Gesundheit als auch bei Krankheit eine wesentliche Rolle. Der Zugang zu neuartigen Glykanstrukturen ermöglicht Fortschritte bei der Antikörpercharakterisierung für die Entdeckung von Biomarkern, die Antikörperentwicklung und das Impfstoffdesign.
Fabienne Weber +4 more
wiley +1 more source
Ocular sequelae of congenital toxoplasmosis in Brazil compared with Europe [PDF]
Toxoplasmic retinochoroiditis appears to be more severe in Brazil, where it is a leading cause of blindness, than in Europe, but direct comparisons are lacking.
Bahia Oliveira LM +37 more
core +1 more source
This review bridges ancestral indigenous knowledge with modern pharmacology, summarizing the phytochemistry and antimicrobial properties of essential oils from seven native American species. It highlights their significant activity against bacterial, fungal and parasitic pathogens, emphasizing their potential as sustainable therapeutic and agricultural
Arley Rey Páez +2 more
wiley +1 more source
Phosphatidylinositol 3-monophosphate is involved in Toxoplasma apicoplast biogenesis [PDF]
Apicomplexan parasites cause devastating diseases including malaria and toxoplasmosis. They harbour a plastid-like, non-photosynthetic organelle of algal origin, the apicoplast, which fulfils critical functions for parasite survival.
Henri J Vial +48 more
core +2 more sources
PCR assays for detection of Toxoplasma gondii infection in Iranian camels (Camelus dromedarius) of Yazd province [PDF]
The protozoan parasite Toxoplasma gondii is one the most important zoonotic pathogens. Therefore, in the current pilot study a total of 50 Iranian one-humped camels of both sexes and different ages that were kept by local farmers in Yazd province of Iran
alireza sazmand +5 more
doaj
Adaptive Immunity in Marsupials
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol +2 more
wiley +1 more source
What new cell biology findings could bring to therapeutics: is it time for a phenome-project in Toxoplasma gondii? [PDF]
"If you know the enemy and know yourself, you need not fear the result of a hundred battles. If you know yourself but not the enemy, for every victory gained you will also suffer a defeat" (SunTzu the Art of War, 544-496 BC).
Meissner, M. +5 more
core +1 more source
Background Toxoplasmosis is caused by an obligatory intracellular coccidian protozoan organism, Toxoplasma gondii. It has a worldwide distribution, affecting one-third of the world population.
Barnabas Achaw +6 more
doaj +1 more source

