Results 21 to 30 of about 82,548 (220)

Characterization of a Fungal Modular Polyketide Synthase System Reveals an Unusual Strategy for Polyketide Chain Initiation

Angewandte Chemie, EarlyView.
Fungal modular polyketide synthases (PKSs) remain largely unexplored. Functional characterization of the LasC/LasD assembly line established its role in strasseriolide C biosynthesis and suggested an unexpected strategy for chain initiation, in which a malonyl unit is transferred from the module 2 acyl carrier protein (ACP) domains to the loading ACP ...
Qiaolin Ji, Chao Peng, Shuhan He, Bin‐Tao Peng, Wei‐Guang Wang, Yudai Matsuda   +5 more
wiley   +2 more sources

Salicylanilide Inhibitors of Toxoplasma gondii [PDF]

Journal of Medicinal Chemistry, 2012
Toxoplasma gondii (T. gondii) is an apicomplexan parasite that can cause eye disease, brain disease, and death, especially in congenitally infected and immune-compromised people. Novel medicines effective against both active and latent forms of the parasite are greatly needed.
Fomovska, Alina, Wood, Richard D., Mui, Ernest, Dubey, Jitenter P., Ferreira, Leandra R., Hickman, Mark R., Lee, Patricia J., Leed, Susan E., Auschwitz, Jennifer M., Welsh, William J., Sommerville, Caroline, Woods, Stuart, Roberts, Craig, Mcleod, Rima   +13 more
openaire   +4 more sources

The Toxoplasma gondii Plastid replication and Repair Enzyme complex, PREX [PDF]

, 2009
A plastid-like organelle, the apicoplast, is essential to the majority of medically and veterinary important apicomplexan protozoa including Toxoplasma gondii and Plasmodium.
Chen, C-Y., Henriquez, F L, Roberts, C. W., Chen, C.Y., Barrett, M.P., Chen, C-Y, Barrett, M. P., Roberts, C W, Henriquez, F. L., Doerig, C., Roberts, C.W., Roberts, Craig, Mukhopadhyay, A, Chen, C.-Y., Mukhopadhyay, A., Henriquez, F.L., Barrett, M P, Doerig, C   +17 more
core   +2 more sources

Identification of TgCBAP, a novel cytoskeletal protein that localizes to three distinct subcompartments of the toxoplasma gondii pellicle [PDF]

, 2014
This work was supported by US Public Health Service grant AI054961 (GEW).The cytoskeletons of Toxoplasma gondii and related apicomplexan parasites are highly polarized, with apical and basal regions comprised of distinct protein complexes.
Lucas D Tilley, Shruthi Krishnamurthy (571344), Nicholas J. Westwood (254891), Shruthi Krishnamurthy, Gary E. Ward (208054), Tilley, Lucas D., Lucas D. Tilley (208044), Nicholas J Westwood, Krishnamurthy, Shruthi, Gary E Ward, Westwood, Nicholas J., Ward, Gary E., Tilley Lucas D., Westwood Nicholas J., Krishnamurthy Shruthi, Ward Gary E., Westwood, Nicholas J.; id_orcid   +16 more
core   +2 more sources

Respon Imun Terhadap Infeksi Toxoplasma Gondii

Jurnal Kesehatan Andalas, 2020
Toxoplasma gondii merupakan parasit golongan protozoa intraseluler yang menyebabkan penyakit zoonosis yaitu toksoplasmosis. Gejala toksoplasmosis dapat berlangsung tanpa gejala hingga menimbulkan gangguan neurologis berat bahkan kematian pada individu ...
Selfi Renita Rusjdi
doaj   +1 more source

Ocular sequelae of congenital toxoplasmosis in Brazil compared with Europe [PDF]

, 2008
Toxoplasmic retinochoroiditis appears to be more severe in Brazil, where it is a leading cause of blindness, than in Europe, but direct comparisons are lacking.
Bahia Oliveira LM, Bahia-Oliveira Lilian M. G., Bahia-Oliveira, LM, Wallon M, Martine Wallon, Lilian M G Bahia-Oliveira, Petersen E, Miles R Stanford, Wallon Martine, Stanford MR, Ruth E Gilbert, Tan, HK, Freeman, K, Katherine Freeman, Stanford Miles R., Lago, EG, Lago EG, Hooi Kuan Tan, Stanford, MR, Tan Hooi Kuan, Freeman K, Gilbert RE, Tan HK, European Multicentre Study on Congenital T.o.x.o.p.l.a.s.m.o.s.i.s., Freeman Katherine, Gilbert, RE, Eskild Petersen, Gilbert Ruth E., European Multicentre Study on Congenital Toxoplasmosis (EMSCOT), Buffolano Wilma, Wilma Buffolano, Petersen, E, Lago Eleonor G., BUFFOLANO, WILMA, Eleonor G Lago, Buffolano, W, Wallon, M, Petersen Eskild, M. R. Stanford, N. Ferret, R. E. Gilbert, S. Rommand, Lago, Eleonor G, A. Prusa, Bahia-Oliveira, Lilian M G, H. K. Tan, P. M. Remmer, M. -H. Bessieres, J Franck, M. Wallon, D. Schmidt, Freeman, Katherine, E. Issert, E. G. Lago, B. Evengard, L. M. G. Bahia-Oliveira, Tan, Hooi Kuan, H. Pelloux, A. M. Wilken de Abreu Oliveira, G. Malm, Wallon, Martine, E. Neto, K. Freeman, P. Bastien, H. Dumon, P. Marty, Gilbert, Ruth E, Stanford, Miles R, R. G. Peixe, C. Bost-Bru, A. Pollak, Petersen, Eskild, M. Cortina-Borja, V. Savasi, W. Buffolano, E. Semprini, J. Melamed, E. Petersen, P. Thulliez, Evengård, Birgitta,, C. Chemla, H. Fricker-Hidalgo, F. Peyron, M. Hayde   +83 more
core   +1 more source

Studies on a murine model of congenital toxoplasmosis : vertical disease transmission only occurs in BALB/c mice infected for the first time during pregnancy [PDF]

, 1992
The incidence of congenital toxoplasmosis was determined by an ELISA in the litters of BALB/c mice which had been infected 8 weeks before mating, on day 12 of pregnancy, or on both these occasions.
Roberts, C W, Alexander, J, Roberts, Craig   +2 more
core   +3 more sources

Prenatal Toxoplasma gondii [PDF]

Clinical Infectious Diseases, 2011
(See the article by Boyer et al, on pages 1081–9.) One of the first lessons regarding congenital infections taught to third-year medical students on obstetrics and reinforced during their pediatric rotations are the variety and pathogenesis of perinatal viral and parasitic infections that can affect pregnant women and their fetuses. From the time of
openaire   +2 more sources

Immunity Status of Blood Donors Regarding Toxoplasma gondii Infection in a Low-Income District of Abidjan, Côte d’Ivoire, West Africa

Journal of Immunology Research, 2016
Background. Toxoplasmosis is a widespread cosmopolitan anthropozoonosis, which affects more than a third of the world population. Except the modes of transmission well known, Toxoplasma gondii can be transmitted during transplantation or blood ...
Liliane Siransy, Sery Romuald Dasse, Serge Pacôme Dou Gonat, Antoinette Legbedji, Koffi N’guessan, Patricia Ama Kouacou, Richard Yeboah, Hervé Menan   +7 more
doaj   +1 more source

The Seroprevalence of Anti-Toxoplasma Gondii IgG and IgM Antibodies in Serum Samples Referred to Educational Hospitals of Abadan [PDF]

مجله دانشکده پزشکی اصفهان
Background: Toxoplasma gondii is an obligate apicomplexan parasite and it is stated that one-third of the world population are seropositive for the antibodies against the parasite.
Shahrzad Soltani, Hadi Moghaddam, Maghsoudi Fatemeh, Sanaz Tavakoli   +3 more
doaj   +1 more source