Results 61 to 70 of about 159,524 (313)

A Systematic Approach to Analyze T Cell Migration: Application to Mouse Melanoma Tumors

Advanced Therapeutics, EarlyView.
The results show that a minimum of two migration speeds can be rigorously identified from the data with cells switching between a fast, persistent migratory state, and a slow, random migration state. These results will help in identifying genetic factors that influence rapid migration, among other applications, such as quality control for CAR‐T cell ...
Nikolaos Memmos, Jason S. Mitchell, Brian T. Fife, David Masopust, David J. Odde   +4 more
wiley   +1 more source

Sero-prevalence of Toxoplasma gondii and associated risk factors among psychiatric outpatients attending University of Gondar Hospital, Northwest Ethiopia

BMC Infectious Diseases, 2019
Background Toxoplasmosis is caused by an obligatory intracellular coccidian protozoan organism, Toxoplasma gondii. It has a worldwide distribution, affecting one-third of the world population.
Barnabas Achaw, Habtie Tesfa, Ayalew Jejaw Zeleke, Ligabaw Worku, Ayenew Addisu, Niguse Yigzaw, Yalewayker Tegegne   +6 more
doaj   +1 more source

Human impact on the diversity and virulence of the ubiquitous zoonotic parasite Toxoplasma gondii

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance A majority of emerging infectious diseases in humans are transmitted from animals. It is generally agreed that our behavior can influence our exposure to such pathogens, but little is known regarding our role in shaping evolution in such ...
E. K. Shwab, P. Saraf, Xing-Quan Zhu, Dong‐Hui Zhou, Brent M. McFerrin, D. Ajzenberg, G. Schares, Kenneth Hammond-Aryee, P. V. van Helden, Steven A. Higgins, Richard W. Gerhold, Benjamin M. Rosenthal, Xiaopeng Zhao, J. Dubey, C. Su   +14 more
semanticscholar   +1 more source

Novel components of the Toxoplasma inner membrane complex revealed by BioID. [PDF]

, 2015
UNLABELLED:The inner membrane complex (IMC) of Toxoplasma gondii is a peripheral membrane system that is composed of flattened alveolar sacs that underlie the plasma membrane, coupled to a supporting cytoskeletal network. The IMC plays important roles in
Bell, Hannah N, Bentolila, Laurent A, Bradley, Peter J, Chen, Allan L, Huang, Amy S, Kim, Elliot W, Moon, Andy S, Rashoff, Andrew Q, Toh, Justin Y, Van, Christina, Vashisht, Ajay A, Wohlschlegel, James A   +11 more
core   +3 more sources

Genome‐Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms–Fish Hosts System and Drug Target Identification

Advanced Science, EarlyView.
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang, Jie‐Mei Zhao, Chuan‐Yu Xiang, Yi‐Wen Ma, Hong‐Peng Lei, Yu‐Ying Shi, Shun Zhou, Xiaofei Zeng, Jinsong Chen, Fei Liu, Benhe Zeng, Rui Song, Ye Hu, Feng Zhang, Xiang Liu, Wen‐Xiang Li, Gui‐Tang Wang, Ivan Jakovlić   +17 more
wiley   +1 more source

Ocorrência de anticorpos anti-Toxoplasma gondii em ovinos das áreas urbanas e periurbanas de Curitiba, Paraná Occurrence of anti-Toxoplasma gondii antibodies in ovine from urban and periurban areas from Curitiba, Parana State

Revista Brasileira de Parasitologia Veterinária, 2009
Com o objetivo de avaliar a ocorrência da infecção por Toxoplasma gondii, em ovinos das regiões periurbana e urbana do município de Curitiba, Paraná, Região Sul do Brasil, foram coletadas amostras de sangue de 167 ovinos, de três rebanhos.
Vanete Thomaz Soccol, Edilene A. de Castro, Tatiana Louise Gazda, Guilherme Garcia, Richartz Rosaria R. T. B., Dittrich Rosangela Locatelli   +5 more
doaj   +1 more source

Pyruvate Homeostasis as a Determinant of Parasite Growth and Metabolic Plasticity in Toxoplasma gondii

mBio, 2019
Toxoplasma gondii infects almost all warm-blooded animals, and metabolic flexibility is deemed critical for its successful parasitism in diverse hosts. Glucose and glutamine are the major carbon sources to support parasite growth. In this study, we found
N. Xia, Shu-Yun Ye, Xiaohan Liang, Pu Chen, Yanqin Zhou, R. Fang, Junlong Zhao, N. Gupta, Shuzhen Yang, Jing Yuan, B. Shen   +10 more
semanticscholar   +1 more source

In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis. [PDF]

, 2016
UnlabelledToxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite secretes an array of dense granule proteins (GRAs) into ...
Bell, Hannah N, Bradley, Peter J, Coppens, Isabelle, Kim, Elliot W, Lin, Andrew H, Nadipuram, Santhosh M, Vashisht, Ajay A, Wohlschlegel, James A   +7 more
core   +2 more sources

The ultrastructure of Toxoplasma gondii

, 2007
Electron microscopy has been an important tool for understanding the biology and ultrastructure of Toxoplasma gondii. As an obligate intracellular parasite, T. gondii has evolved specialized organelles for invasion and successful intracellular parasitism.
Ferguson, D, Dubremetz, J
openaire   +3 more sources

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source