Results 101 to 110 of about 216,061 (290)

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Post-synaptic Release of the Neuronal Tissue-Type Plasminogen Activator (tPA)

Frontiers in Cellular Neuroscience, 2019
The neuronal serine protease tissue-type Plasminogen Activator (tPA) is an important player of the neuronal survival and of the synaptic plasticity. Thus, a better understanding the mechanisms regulating the neuronal trafficking of tPA is required to ...
Sophie Lenoir, Alexandre Varangot, Laurent Lebouvier, Thierry Galli, Yannick Hommet, Denis Vivien, Denis Vivien   +6 more
doaj   +1 more source

Connexin 43‐Enriched Vesicles Improve Synchronization in hiPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Plasma membrane‐derived Connectosomes enriched in connexin‐43 are produced from donor hiPSCs and applied to hiPSC‐derived cardiomyocytes (hiPSC‐CMs). Connexin‐43 channels on Connectosomes remain functional, strengthening intercellular electrochemical coupling and increasing network synchronization over time.
Nima Momtahan, Anna K. McClain, Andrea Trementozzi, Sogu Sohn, Lingxia Qiao, Chi Zhao, Padmini Rangamani, Jeanne C. Stachowiak, Janet Zoldan   +8 more
wiley   +1 more source

The Emerging Parkinson's Disease Oxylipin‐Ome

Advanced Science, EarlyView.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

Trade Promotion Authority (TPA) Renewal: Core Labor Standards Issues: A Brief Overview [PDF]

, 2007
[Excerpt] This report is a brief overview of key issues addressed in CRS Report RL33864, Trade Promotion Authority (TPA) Renewal: Core Labor Standards Issues.
Bolle, Mary Jane
core   +2 more sources

Young's modulus of Graphene: a molecular dynamics study

, 2009
The Young's modulus of graphene is investigated through the intrinsic thermal vibration in graphene which is `observed' by molecular dynamics, and the results agree quite well with the recent experiment [Science \textbf{321}, 385 (2008)].
A. D. Polyanin, Baowen Li, Jian-Sheng Wang, Jin-Wu Jiang, L. D. Landau   +4 more
core   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

Novel Situations of Endothelial Injury in Stroke — Mechanisms of Stroke and Strategy of Drug Development: Novel Mechanism of the Expression and Amplification of Cell Surface–Associated Fibrinolytic Activity Demonstrated by Real-Time Imaging Analysis

Journal of Pharmacological Sciences, 2011
.: Vascular endothelial cells (VECs) secrete tissue plasminogen activator (tPA) in an active form and thus its facilitated secretion directly enhances fibrinolytic activity.
Yuko Suzuki, Tetsumei Urano
doaj   +1 more source

Two-Photon Spectroscopy Between States of Opposite Parities

, 1995
Magnetic- and electric-dipole two-photon absorption (MED-TPA), recently introduced as a new spectroscopic technique for studying transitions between states of opposite parities, is investigated from a theoretical point of view.
A.G. Makhanek, D. Fröhlich, G.E. Stedman, J. Sztucki, J. Sztucki, J.C. G ^acon, J.C. G ^acon, J.D. Axe, Jr., J.J. Hopfield, M. Daoud, M. Daoud, M. Daoud, M. Inoue, M. Kibler, M. Kibler, M. Kibler, M.R. Kibler, R.C. Leavitt, S.K. Gayen, T.R. Bader   +19 more
core   +2 more sources