Results 101 to 110 of about 105,732 (293)

Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms

open access: yesNeurobiology of Disease, 2007
Alzheimer’s disease (AD) is the most common form of neurodegenerative disorder in the ageing population. It is characterized by the cerebral accumulation of toxic amyloid-beta peptide assemblies (Aβ).
Mathias Cacquevel   +9 more
doaj   +1 more source

APPF TPA phenotyping dataset: UA TPA (Berger) - Wheat (UniformityTrial)

open access: yes, 2023
Images and data from wheat phenotyping studies (UniformityTrial) performed at the APPF Plant Accelerator (TPA), University of Adelaide, on behalf of UA TPA (Berger) ending 2016-06 ...
Bettina Berger (4191988)
core   +1 more source

Efficient Polaron Recombination and Fast Energy Transfer in a Deep Blue Phosphorescent Pt(II) Complex via Covalently Fused p‐Type Host

open access: yesAdvanced Science, EarlyView.
Achieving high‐efficiency deep‐blue phosphorescent OLEDs is limited by intermolecular kinetic bottlenecks. We overcome this using a single‐molecule fused emitter architecture, Pt‐SP‐tCz, combining a p‐type host and Pt(II) dopant. This design enables zero‐radius intramolecular energy transfer (ZRIET) and a novel ZETPLEX mechanism.
You Na Song   +9 more
wiley   +1 more source

The Influence of Fluorination on Nano-Scale Phase Separation and Photovoltaic Performance of Small Molecular/PC71BM Blends

open access: yesNanomaterials, 2016
To investigate the fluorination influence on the photovoltaic performance of small molecular based organic solar cells (OSCs), six small molecules based on 2,1,3-benzothiadiazole (BT), and diketopyrrolopyrrole (DPP) as core and fluorinated phenyl (DFP ...
Zhen Lu   +7 more
doaj   +1 more source

APPF TPA phenotyping dataset: UA TPA (Garnett, Hansen) - Wheat (hydro)

open access: yes, 2023
Images and data from wheat phenotyping studies (hydro) performed at the APPF Plant Accelerator (TPA), University of Adelaide, on behalf of UA TPA (Garnett, Hansen) ending 2016-10 ...
Trevor Garnett (15921305)
core   +1 more source

D–A Type Perylene Micelles With Synergistic Charge/Energy Transfer for Dual‐Path ROS Generation and Enhanced Photocatalysis

open access: yesAdvanced Science, EarlyView.
Dual‐state activation of singlet and triplet excitons is achieved in perylene‐based nanomicelles via donor engineering. By synergistically pairing charge transfer with energy transfer pathways, while concurrently enabling pollutant pre‐enrichment, this strategy establishes spatial coupling between efficient ROS generation and rapid mineralization ...
Chenfan Xie   +8 more
wiley   +1 more source

Intra-Arterial Tissue Plasminogen Activator for Central Retinal Artery Occlusion

open access: yesClinical Ophthalmology, 2021
Ethan K Sobol,1,2 Yu Sakai,3 Danielle Wheelwright,3 Carl S Wilkins,1,2 Amanda Norchi,1 Michael G Fara,4 Christopher Kellner,3 James Chelnis,1 J Mocco,3 Richard B Rosen,1,2 Reade A De Leacy,3 Gareth MC Lema1,2 1Department of Ophthalmology, Icahn School of
Sobol EK   +11 more
doaj  

tPA in the Central Nervous System: Relations Between tPA and Cell Surface LRPs

open access: yesRecent Patents on Endocrine, Metabolic & Immune Drug Discovery, 2012
A growing body of evidence has implicated the plasminogen activating system in various aspects of neurophysiology and pathophysiology. In ischemic stroke, blood-brain barrier (BBB) regulations, typically involving matrix metalloproteinases (MMPs), inhibitors tissue inhibitors of metalloproteinases (TIMPs) and the low density lipoprotein receptor ...
Ortolano, Saida, Spuch Calvar, Carlos
openaire   +3 more sources

APPF TPA phenotyping dataset: UA TPA (Garnett, Hansen) - Wheat

open access: yes, 2023
Images and data from wheat phenotyping studies performed at the APPF Plant Accelerator (TPA), University of Adelaide, on behalf of UA TPA (Garnett, Hansen) ending 2015-10 ...
Trevor Garnett (15921305)
core   +1 more source

Reversing Temozolomide Resistance in Glioblastoma Based on Cuproptosis‐Mediated Positive Feedback Loop

open access: yesAdvanced Science, EarlyView.
To effectively reverse TMZ resistance, this work proposes a cuproptosis‐mediated positive feedback loop that integrates mitochondrial dysfunction, ATP depletion, AMPK‐p53 signaling, and glycolytic inhibition, ultimately amplifying cell death. This cuproptosis‐mediated feedback loop simultaneously disrupts multiple resistance pathways in GBM, including ...
Wenjie Feng   +9 more
wiley   +1 more source

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