Results 111 to 120 of about 105,732 (293)

Pathogenesis of respiratory failure in COVID-19 due to coagulopathy and endothelial dysfunction

Acta Biomedica Scientifica
Respiratory failure is known to be the main clinical manifestation of COVID-19. However, the mechanism of its development has not been sufficiently studied.
T. O. Burdienko
doaj   +1 more source

APPF TPA phenotyping dataset: UA TPA (Berger) - Various (leaf tracking)

, 2023
Images and data from various phenotyping studies (leaf tracking) performed at the APPF Plant Accelerator (TPA), University of Adelaide, on behalf of UA TPA (Berger) ending 2017-07 ...
Bettina Berger (4191988)
core   +1 more source

Super‐Multiplexed Label‐Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation

Advanced Science, EarlyView.
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li, Xia Chen, Yujuan Qi, Chen Qiao, Qiuru Huang, Dan Zhao, Weiyi Qian, Li Di, Yi Shi, Xiangqi Hu, Yueyue Shao, Kehan Wang, Zhiyu Tang‐Yang, Hanzhi Zang, Yuwen Du, Anran Dong, Jinxiong Feng, Jiayun Chen, Ying Zheng, Xiaofang Tan, Xiaoyu Zhao, Zhonghua Shi, Bo Zheng, Jun Yu   +23 more
wiley   +1 more source

Stroke Vasc Neurol [PDF]

IntroductionIntravenous tissue plasminogen activator (IV tPA) is a globally recommended treatment for acute ischemic stroke patients. We examined IV tPA use among patients aged 18-64 years with a primary diagnosis acute ischemic stroke in the US and ...

core  

TPA : termination proved automatically TPA: Termination Proved Automatically

, 2020
TPA is a tool for proving termination of term rewrite systems (TRSs) in a fully automated fashion. The distinctive feature of TPA is the support for relative termination and the use of the technique of semantic labelling with natural numbers.
Adam Koprowski
core  

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

Advanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang, Jiaxin Tian, Xiaolong Zhu, Xiao Li, Xiangshu Qiu, Yuanyuan Li, Ben Zhong Tang, Ning Shi   +7 more
wiley   +1 more source

A novel use of tissue plasminogen activator in PreserFlo Microshunt obstructed by fibrin and/or blood

Indian Journal of Ophthalmology. Case Reports
To report the novel use of tPA in PreserFlo MicroShunt obstructed by fibrin and/or blood. PreserFlo MicroShunts are used in the management of medically uncontrolled Primary Open Angle Glaucoma (POAG). Hyphaema is a common complication of glaucoma surgery.
Rashmi Rao, Fook C Lam, Beverly Cheung
doaj   +1 more source

Toward Material‐Specific Peptides From in Silico Guided Peptide Engineering to Target PET in the Presence of PS

Advanced Science, EarlyView.
This work presents a computational–experimental strategy to engineer material‐binding peptides toward polymer specificity. Molecular dynamics simulations identified residues driving polystyrene binding, enabling targeted substitutions that greatly reduced polystyrene affinity while preserving PET binding.
Julian Luka, Marian Bienstein, Jonas Berger, Ulrich Schwaneberg   +3 more
wiley   +1 more source

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

Post-synaptic Release of the Neuronal Tissue-Type Plasminogen Activator (tPA)

Frontiers in Cellular Neuroscience, 2019
The neuronal serine protease tissue-type Plasminogen Activator (tPA) is an important player of the neuronal survival and of the synaptic plasticity. Thus, a better understanding the mechanisms regulating the neuronal trafficking of tPA is required to ...
Sophie Lenoir, Alexandre Varangot, Laurent Lebouvier, Thierry Galli, Yannick Hommet, Denis Vivien, Denis Vivien   +6 more
doaj   +1 more source