Results 131 to 140 of about 216,061 (290)

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

Electrochemical and Optical Properties of D-A-A-A-D Azomethine Triad and Its NIR-Active Polymer

Molecules
The azomethine TPA-(BTZ)3-TPA with a donor–acceptor–acceptor–acceptor–donor structure has been synthesized and characterized. Azomethine TPA-(BTZ)3-TPA exhibited luminescence properties and a positive solvatochromic effect.
Mateusz Roszyk, Monika Wałęsa-Chorab
doaj   +1 more source

Neuronal conversion of single-chain tissue-type plasminogen activator into its two-chain form: implications in neurodevelopment, learning, and memory

Cell Death and Disease
Tissue-type plasminogen activator (tPA) is a serine protease expressed in the central nervous system (CNS) that exhibits various effects, from neurodevelopment to learning and memory processes. tPA is secreted in its single-chain form (sc-tPA) and can be
Hortense Triniac, Simon Lebatard, Valerie Roussel, Charlotte Lechevallier, Laurent Lebouvier, Denis Vivien, Benoit D. Roussel   +6 more
doaj   +1 more source

TPA in acute stroke [PDF]

European Heart Journal, 1997
W, Hacke, J, Marler
openaire   +2 more sources

The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity

Journal of Neuroinflammation
The thrombolytic protease tissue plasminogen activator (tPA) is expressed in the CNS, where it regulates diverse functions including neuronal plasticity, neuroinflammation, and blood-brain-barrier integrity.
Daniel Torrente, Enming J. Su, Alí Francisco Citalán-Madrid, Gerald P. Schielke, Daniel Magaoay, Mark Warnock, Tamara Stevenson, Kris Mann, Flavie Lesept, Nathalie Delétage, Manuel Blanc, Erin H. Norris, Denis Vivien, Daniel A. Lawrence   +13 more
doaj   +1 more source

OTV bearing deflection investigation [PDF]

The primary goal of the Bearing Deflectometer Investigation was to gain experience in the use of fiber optic displacement probe technology for bearing health monitoring in a liquid hydrogen turbo pump.
Diepenbrock, R. T., Millis, M. G., Reimer, B. L.   +2 more
core   +1 more source

Recent Advances in Stimulated Brillouin Scattering in Integrated Photonics

Advanced Physics Research, EarlyView.
This review systematically surveys recent advances in stimulated Brillouin scattering (SBS) within integrated photonics. It begins by elucidating the fundamental mechanisms of stimulated coupling between photons and acoustic phonons in nanoscale waveguides, enhanced by the photoelastic and moving boundary effects.
Songyue Liu, Qi Lu, Pan Hu, Yuan Zhong, Yu He, Yaojing Zhang, Young‐Ik Sohn, Yikai Su, Lu Sun   +8 more
wiley   +1 more source

Spoiled holidays: Damages for disappointment or distress [PDF]

, 2004
Generally damages for disappointment or distress following a breach of contract will not be awarded to the innocent party under common law. However where the object of the contract is to provide relaxation or enjoyment, for example, an ocean cruise or a ...
Evans, Philip J
core   +1 more source

The skeleton of the green Iguana iguana (Squamata: Iguanidae) and its intraspecific morphological variation

The Anatomical Record, EarlyView.
Abstract The green iguana (Iguana iguana) is an iguanine lizard with herbivorous and arboreal habits, whose distribution spans through South America, Central America to the south of North America. Although the genus Iguana is well‐known, the species still lacks a comprehensive and up‐to‐date anatomical study, particularly addressing the axial skeleton,
Vieno Rosa, Marcos Vinícius Coelho, Camila Cupello   +2 more
wiley   +1 more source

Practice, knowledge and attitude of physicians and pharmacists towards the spontaneous reporting system of adverse drug reactions in Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Introduction Introduction Reporting adverse drug reactions (ADRs) is essential for detecting drug risks. Despite legal obligations in Switzerland, underreporting remains an issue. This study assessed practice, knowledge and attitudes towards the spontaneous ADR reporting system among physicians and pharmacists.
Fiona A. Strobel, Thomas Stammschulte, Patrick E. Beeler   +2 more
wiley   +1 more source