Results 151 to 160 of about 92,920 (301)

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity

Journal of Neuroinflammation
The thrombolytic protease tissue plasminogen activator (tPA) is expressed in the CNS, where it regulates diverse functions including neuronal plasticity, neuroinflammation, and blood-brain-barrier integrity.
Daniel Torrente, Enming J. Su, Alí Francisco Citalán-Madrid, Gerald P. Schielke, Daniel Magaoay, Mark Warnock, Tamara Stevenson, Kris Mann, Flavie Lesept, Nathalie Delétage, Manuel Blanc, Erin H. Norris, Denis Vivien, Daniel A. Lawrence   +13 more
doaj   +1 more source

Electrochemical and Optical Properties of D-A-A-A-D Azomethine Triad and Its NIR-Active Polymer

Molecules
The azomethine TPA-(BTZ)3-TPA with a donor–acceptor–acceptor–acceptor–donor structure has been synthesized and characterized. Azomethine TPA-(BTZ)3-TPA exhibited luminescence properties and a positive solvatochromic effect.
Mateusz Roszyk, Monika Wałęsa-Chorab
doaj   +1 more source

How to Navigate Disrupted Business Models in the 21st Century: At the Crossroads of the Circular Economy and the Industry 4.0 Transition

Business Strategy and the Environment, EarlyView.
ABSTRACT Our planet faces a critical crisis, with pollution, resource depletion and biodiversity loss surpassing sustainable limits. Businesses must address these challenges, with the circular economy and Industry 4.0 offering transformative potential through closed‐loop systems, regenerative solutions and advanced technologies.
Agnes Toth‐Peter, Rui Torres de Oliveira, Shane Mathews, Leonie Barner   +3 more
wiley   +1 more source

Neuronal conversion of single-chain tissue-type plasminogen activator into its two-chain form: implications in neurodevelopment, learning, and memory

Cell Death and Disease
Tissue-type plasminogen activator (tPA) is a serine protease expressed in the central nervous system (CNS) that exhibits various effects, from neurodevelopment to learning and memory processes. tPA is secreted in its single-chain form (sc-tPA) and can be
Hortense Triniac, Simon Lebatard, Valerie Roussel, Charlotte Lechevallier, Laurent Lebouvier, Denis Vivien, Benoit D. Roussel   +6 more
doaj   +1 more source

Artificial Intelligence Tools for Carbon Nanotube Research: Opportunities From Synthesis to Applications

Carbon and Hydrogen, EarlyView.
Artificial intelligence tools are reshaping carbon nanotube research by connecting synthesis, characterization, and application‐oriented design. This review outlines how supervised learning, deep learning, Bayesian optimization, and large language models accelerate data extraction, experiment planning, and structure–property discovery for carbon ...
Yanlong Zhao, Fei Wang, Qixuan Cai, Aike Xi, Kangkang Wang, Khaixien Leu, Rufan Zhang   +6 more
wiley   +1 more source

tPA activity measures.

, 2013
(A) Human tPA but not saline activates mouse plasminogen. In this assay, tPA converts plasminogen to plasmin, then plasmin converts D-Val-Leu-Lys-7-Amino-4-Methylcoumarin to a fluorescent product, which was measured over 1 hr at 5 minute intervals using ...
Flor A. Cianchetti (280825), Christian Foerch (149410), Frieder Schlunk (280822), Eng H. Lo (112154), Kazim Yigitkanli (280829), Chris B. Schaffer (155846), Arne Lauer (280824), Ken Arai (280828), Emiri Mandeville (280827), Nathanael L. Rosidi (280821), Helmuth Steinmetz (149409), Xiaoying Wang (30853), Klaus van Leyen (280831), Xiang Fan (280830)   +13 more
core   +1 more source

Effects of Wheat Bran‐Derived Arabinoxylan Oligosaccharides on Dough and Noodle‐Making Properties

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives This study investigates the structural modifications of arabinoxylan (AX) through enzymatic hydrolysis and evaluates the potential application of arabinoxylan oligosaccharides (AXOS) as functional ingredients in wheat noodles, contrasting their effects with those of native AX.
Yunseo Kim, Meera Kweon
wiley   +1 more source

MXenes as a Versatile Platform for High‐Energy‐Density Asymmetric Supercapacitors

Carbon Energy, EarlyView.
MXenes with high conductivity and tunable surface chemistry are reviewed as advanced electrodes for asymmetric supercapacitors. MAX‐phase synthesis, surface and interlayer engineering, defect modulation, and composite designs are discussed, highlighting enhanced ion transport, pseudocapacitance, energy density, cycling stability, and sustainable routes
Seul‐Yi Lee, Jagadis Gautam, Shrikant Vaiju Sadavar, Soo‐Jin Park   +3 more
wiley   +1 more source