Results 161 to 170 of about 270,020 (316)

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

open access: yesAnnals of Neurology, EarlyView.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito   +10 more
wiley   +1 more source

Individualized Treatment in Distal and Medium Vessel Occlusion Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model

open access: yesAnnals of Neurology, EarlyView.
Objective The optimal treatment for distal medium vessel occlusion (DMVO) stroke remains uncertain, and evidence comparing endovascular therapy (EVT) with medical management (MM) is limited. We aimed to develop and validate a predictive modeling tool to assess individual treatment benefit in DMVO stroke using explainable counterfactual treatment ...
Mohamed F. Doheim   +14 more
wiley   +1 more source

Atomically Thin Sieves: Two‐Dimensional Materials for Membrane Separation

open access: yesAdvanced Physics Research, EarlyView.
Atomically thin membranes derived from 2D materials overcome the inherent selectivity‐permeability trade‐off in conventional separation technologies. This perspective elucidates transport mechanisms for gases, water, and ions, surveys fabrication strategies including top‐down pore engineering and bottom‐up synthesis, highlights recent experimental and ...
Yiran Gong, Pengzhan Sun, Yu Ji
wiley   +1 more source

The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons

open access: yesCell Death and Disease
Recombinant tissue-type plasminogen activator (r-tPA/Actilyse) stands as the prevailing pharmacological solution for treating ischemic stroke patients, of whom because their endogenous circulating tPA alone is not sufficient to rescue reperfusion and to ...
Paul Prunotto   +5 more
doaj   +1 more source

TNK-tPA (tenecteplase).

open access: yesIndian heart journal, 2010
Management of acute myocardial infarction (AMI) has undergone seismic changes in the last two decades, primarily with the global availability of thrombolytic agents and with the burgeoning use of Primary PCI. Application of these two modalities has dramatically reduced both the mortality and morbidity from AMI.
Sameer, Mehta   +4 more
openaire   +1 more source

The skeleton of the green Iguana iguana (Squamata: Iguanidae) and its intraspecific morphological variation

open access: yesThe Anatomical Record, EarlyView.
Abstract The green iguana (Iguana iguana) is an iguanine lizard with herbivorous and arboreal habits, whose distribution spans through South America, Central America to the south of North America. Although the genus Iguana is well‐known, the species still lacks a comprehensive and up‐to‐date anatomical study, particularly addressing the axial skeleton,
Vieno Rosa   +2 more
wiley   +1 more source

Sustainable and cost‐effective process design for energy‐self‐sufficient ethyl lactate production from sugar mill feedstocks: a techno‐economic approach

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Bio‐based ethyl lactate (EL) can replace several fossil‐derived products owing to its low toxicity, high solvent functionality, and environmental advantages. This study assesses the techno‐economic viability and greenhouse gas (GHG) reduction potential of producing EL from sugarcane A‐molasses and lignocelluloses in an energy self‐sufficient ...
Motshamonyane J. Phasha   +2 more
wiley   +1 more source

Understanding the influence of transfusion and blood loss on tranexamic acid concentration in scoliosis surgery with blood loss

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Tranexamic acid (TXA) stabilizes clot formation by inhibiting fibrin degradation and improves postoperative outcomes. However, rare adverse events (e.g., thrombosis, seizures) warrant dose–risk evaluation. This study examines how perioperative blood loss and transfusion practices affect TXA concentrations during paediatric scoliosis surgery ...
Paula Alexandra Sá   +4 more
wiley   +1 more source

A pH‐responsive charge‐reversal liposome with enhanced biofilm penetration for multimodal synergistic therapy of bacterial infections

open access: yesBMEMat, EarlyView.
This study develops a pH‐responsive, charge‐reversal liposome for treating bacterial biofilm infections. With enhanced penetration capability, the liposome effectively delivers antibacterial agents into biofilms. By integrating photodynamic and photothermal therapies with antibiotics, it significantly eradicates biofilms and accelerates bacteria ...
Ruyue Li   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy