Results 41 to 50 of about 270,020 (316)

Risk of Intracranial Hemorrhage Following Intravenous tPA (Tissue-Type Plasminogen Activator) for Acute Stroke Is Low in Children

open access: yesStroke, 2019
Supplemental Digital Content is available in the text. Background and Purpose— Data regarding the safety and efficacy of intravenous tPA (tissue-type plasminogen activator) in childhood acute arterial ischemic stroke are inadequate.
Catherine Amlie-Lefond   +17 more
semanticscholar   +1 more source

Nonlinear transmission spectroscopy with dual frequency combs [PDF]

open access: yes, 2014
We show how two frequency combs $\mathcal{E}_1$, $\mathcal{E}_2$ can be used to measure single-photon, two-photon absorption (TPA), and Raman resonances in a molecule with three electronic bands, by detecting the radio frequency modulation of the ...
Glenn, Rachel, Mukamel, Shaul
core   +2 more sources

tPA-anchored nanorobots for in vivo arterial recanalization at submillimeter-scale segments

open access: yesScience Advances
Micro/nanorobots provide a promising approach for intravascular therapy with high precision. However, blood vessel is a highly complex system, and performing interventional therapy in those submillimeter segments remains challenging.
Ben Wang   +19 more
semanticscholar   +1 more source

The serum protein levels of the tPA–BDNF pathway are implicated in depression and antidepressant treatment

open access: yesTranslational Psychiatry, 2017
Evidence demonstrates that brain-derived neurotrophic factor (BDNF) has a pivotal role in the pathogenesis of major depressive disorder (MDD). Precursor-BDNF (proBDNF) and mature BDNF (mBDNF) have opposing biological effects in neuroplasticity, and the ...
H. Jiang   +9 more
semanticscholar   +1 more source

Ubiquitin-specific peptidase 3 induces TPA-mediated leukemia cell differentiation via regulating H2AK119ub

open access: yesAnimal Cells and Systems, 2019
Acute myeloid leukemia (AML) is the most common type of leukemia in adults. Owing to the chemotherapy associated side effects and toxicity, it is necessary to find a new mechanism, which can identify new potential therapeutic targets at the molecular ...
Yun-Cheol Chae   +4 more
doaj   +1 more source

Estimation of noise radiation including airborne noise using the in-situ blocked force approach (Proposal of an approximate method and its verification using a simple model)

open access: yesNihon Kikai Gakkai ronbunshu, 2018
This paper proposes a methodology for estimating airborne noise from a mechanical system under the operational conditions by component tests of a certain active subsystem which is a part of the mechanical system and includes all of vibration sources in ...
Yoshihiro SATO, Nobuyuki IWATSUKI
doaj   +1 more source

Metallic Icosahedron Phase of Sodium at Terapascal Pressures [PDF]

open access: yes, 2015
Alkali metals exhibit unexpected structures and electronic behavior at high pressures. Compression of metallic sodium (Na) to 200 GPa leads to the stability of a wide-band-gap insulator with the double hexagonal hP4 structure.
Li, Yinwei   +5 more
core   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Low Expression of PLAT in Breast Cancer Infers Poor Prognosis and High Immune Infiltrating Level

open access: yesInternational Journal of General Medicine, 2021
Xinyang Wang,1,* Dandan Xue,1,* Xiaoxia Zhu,2,* Rui Geng,3 Xin Bao,2 Xiang Chen,2 Tiansong Xia1,4 1Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, People’s Republic of China; 2Department ...
Wang X   +6 more
doaj  

Stroke in the Adolescent Population

open access: yesPediatric Neurology Briefs, 2020
Investigators from 10 French academic centers studied a retrospective cohort of 60 patients aged 10-18 years (mean age 15.2 years) presenting with first-time stroke, as identified from discharge ICD-10 codes.
Ethan J Rosenberg, Jonathan E Kurz
doaj   +1 more source

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