Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of ...
Alejandra Perez +6 more
core
Endothelial protein C receptor is overexpressed in colorectal cancer as a result of amplification and hypomethylation of chromosome 20q [PDF]
, 2017 Endothelial Protein C Receptor (EPCR) is a Major Histocompatibility Complex homologue, with established roles downregulating coagulation and in endothelial protection.
Beggs, Andrew +6 more
core +1 more source
TPD52和TPD52L2在胃癌中异常表达的临床病理特征分析和相关基因共表达意义研究
Zhongguo shiyan zhenduanxue目的 应用生物信息学的方法探讨肿瘤蛋白D52(tumor protein D52,TPD52)和肿瘤蛋白D52样2(tumor protein D52-like 2,TPD52L2)在胃癌中异常表达的临床病理特征，并分析相关基因共表达的意义。方法 基于癌症基因组图谱(The Cancer Genome AHas, TCGA)获取数据，利用R语言软件包比较TPD52和TPD52L2在胃癌组织和癌旁组织中的差异表达与临床病理特征的相关性，并探索与免疫细胞浸润水平的情况，Kaplan ...
高夏青 +6 more
doaj
Substrate Identification of an Oncogenic Kinase: Elucidating the Pathogenesis of a Rare Liver Cancer [PDF]
, 2019 Fibrolamellar Hepatocellular Carcinoma (FLC) is a rare liver cancer with limited treatment options. This cancer primarily affects adolescents and young adults. Our lab has identified a new fusion gene in this cancer called DNAJB1-PRKACA that results from
Jarmel, Melissa
core +1 more source
Genetically Modified T-Cell-Based Adoptive Immunotherapy in Hematological Malignancies [PDF]
, 2017 A significant proportion of hematological malignancies remain limited in treatment options. Immune system modulation serves as a promising therapeutic approach to eliminate malignant cells.
Baixin Ye +7 more
core +2 more sources
Exon array analysis of head and neck cancers identifies a hypoxia related splice variant of LAMA3 associated with a poor prognosis [PDF]
, 2009 The identification of alternatively spliced transcript variants specific to particular biological processes in tumours should increase our understanding of cancer.
Betts, GN +5 more
core +2 more sources
DDoS: A Graph Neural Network based Drug Synergy Prediction Algorithm
, 2022 Background: Drug synergy occurs when the combined effect of two drugs is greater than the sum of the individual drugs' effect. While cell line data measuring the effect of single drugs are readily available, there is relatively less comparable data on ...
Allam, Ahmed +5 more
core
TPD52和TPD52L2在胃癌中异常表达的临床病理特征分析和相关基因共表达意义研究 附视频
Zhongguo shiyan zhenduanxue目的 应用生物信息学的方法探讨肿瘤蛋白D52(tumor protein D52,TPD52)和肿瘤蛋白D52样2(tumor protein D52-like 2,TPD52L2)在胃癌中异常表达的临床病理特征，并分析相关基因共表达的意义。方法 基于癌症基因组图谱(The Cancer Genome AHas, TCGA)获取数据，利用R语言软件包比较TPD52和TPD52L2在胃癌组织和癌旁组织中的差异表达与临床病理特征的相关性，并探索与免疫细胞浸润水平的情况，Kaplan ...
doaj +2 more sources
Verifica di potenziali biomarcatori in pazienti con disturbo bipolare [PDF]
, 2015 Questo lavoro di tesi nasce da uno studio comparativo condotto e pubblicato nel 2014 che ha visto l’utilizzo dell’elettroforesi bidimensionale, accoppiata a spettrofotometria di massa, per caratterizzare e confrontare il contenuto proteico di linfociti ...
PELOSI, ALICE
core
American journal of translational researchGlioblastoma multiforme is the most deadly primary brain tumor and has no effective treatment. Therefore, it is important to identify novel and effective therapies that impede glioma tumorigenesis. MicroRNAs (miRNAs) are helpful analytical biomarkers and may be useful targets for treating multiple human cancers.
Jin, Yu, Shi-Wen, Wu, Wei-Ping, Wu
openaire +1 more source