Results 41 to 50 of about 16,561,111 (163)
Background: Biological molecules such as therapeutic proteins and peptides have provided ample opportunities for further improvements in health and wellbeing.
Patrícia Batista +4 more
doaj +1 more source
Candidalysin triggers epithelial cellular stresses that induce necrotic death
Candidalysin, a potent cytotoxin secreted by the invasive form of the human pathogenic fungus Candida albicans, is capable of inducing necrotic cell death in epithelial cells. Candidalysin remains at the host epithelial cell membrane and causes an increase in the intracellular calcium (Ca2+) concentration, mitochondrial membrane dysfunction (Δψm ...
Mariana Blagojevic +6 more
wiley +1 more source
Slow Turning Lateral Vessel Bioreactor Improves Embryoid Body Formation and Cardiogenic Differentiation of Mouse Embryonic Stem Cells. [PDF]
Embryonic stem cells (ESCs) have the ability to form aggregates, which are called embryoid bodies (EBs). EBs mimic early embryonic development and are commonly produced for cardiomyogenesis.
Tharasanit, T. +12 more
core +2 more sources
The human pathogenic fungus Candida albicans is able to cause epithelial damage. To achieve this, sequential cellular processes are essential: appropriate epithelial adhesion, hyphal extension and invasion, high levels of ECE1 transcription, proper Ece1 processing, ending in candidalysin secretion and accumulation in the invasion pocket. If any of such
Selene Mogavero +13 more
wiley +1 more source
Nanotechnology‐Based Strategies to Evaluate and Counteract Cancer Metastasis and Neoangiogenesis
Nanomaterials can be used as detection and therapeutic agents to combat cancer metastasis and angiogenesis, owing to their unique characteristics which allow tailored and tunable functions. Abstract Cancer metastasis is the major cause of cancer‐related morbidity and mortality.
Özlem Şen +2 more
wiley +1 more source
Abstract Oral lichen planus (OLP) is an immune‐mediated disease of the oral mucosa with idiopathic aetiology. It is frequently treated with topical corticosteroids (applied as gels, mouthwashes, or sprays); however, the mucosal exposure times of topical corticosteroids are short because of removal by the constant flow of saliva and mechanical forces ...
Zulfahmi Said +4 more
wiley +1 more source
Santosh Bashyal,1 Jo-Eun Seo,1 Taekwang Keum,1,2 Gyubin Noh,1,2 Shrawani Lamichhane,1,2 Jeong Hwan Kim,1,2 Chang Hyun Kim,3 Young Wook Choi,3 Sangkil Lee1,2 1College of Pharmacy, Keimyung University, Daegu, Republic of Korea; 2Center for Forensic ...
Bashyal S +8 more
doaj
Cytokine-Mediated Inflammation in the Oral Cavity and Its Effect on Lipid Nanocarriers
Topical drug administration to the oral mucosa proves to be a promising treatment alternative for inflammatory diseases. However, disease-related changes in the cell barrier must be considered when developing such delivery systems.
Carolin Tetyczka +8 more
doaj +1 more source
IL-29 Enhances CXCL10 Production in TNF-α-stimulated Human Oral Epithelial Cells [PDF]
Interleukin-29 (IL-29) is a cytokine belonging to the type III interferon family. It was recently detected in the gingival crevicular fluid of periodontitis patients.
Y. Hosokawa +4 more
semanticscholar +2 more sources
Taekwang Keum,1,2,* Gyubin Noh,1,2,* Jo-Eun Seo,1 Santosh Bashyal,1,2 Dong Hwan Sohn,1 Sangkil Lee1,2 1College of Pharmacy, Keimyung University, Daegu, Republic of Korea; 2Center for Forensic Pharmaceutical Science, Daegu, Republic of Korea&ast ...
Keum T +5 more
doaj

