Results 41 to 50 of about 16,561,111 (163)

Preparation, Characterization and Evaluation of Guar Films Impregnated with Relaxing Peptide Loaded into Chitosan Microparticles

open access: yesApplied Sciences, 2021
Background: Biological molecules such as therapeutic proteins and peptides have provided ample opportunities for further improvements in health and wellbeing.
Patrícia Batista   +4 more
doaj   +1 more source

Candidalysin triggers epithelial cellular stresses that induce necrotic death

open access: yesCellular Microbiology, Volume 23, Issue 10, October 2021., 2021
Candidalysin, a potent cytotoxin secreted by the invasive form of the human pathogenic fungus Candida albicans, is capable of inducing necrotic cell death in epithelial cells. Candidalysin remains at the host epithelial cell membrane and causes an increase in the intracellular calcium (Ca2+) concentration, mitochondrial membrane dysfunction (Δψm ...
Mariana Blagojevic   +6 more
wiley   +1 more source

Slow Turning Lateral Vessel Bioreactor Improves Embryoid Body Formation and Cardiogenic Differentiation of Mouse Embryonic Stem Cells. [PDF]

open access: yes, 2013
Embryonic stem cells (ESCs) have the ability to form aggregates, which are called embryoid bodies (EBs). EBs mimic early embryonic development and are commonly produced for cardiomyogenesis.
Tharasanit, T.   +12 more
core   +2 more sources

Candidalysin delivery to the invasion pocket is critical for host epithelial damage induced by Candida albicans

open access: yesCellular Microbiology, Volume 23, Issue 10, October 2021., 2021
The human pathogenic fungus Candida albicans is able to cause epithelial damage. To achieve this, sequential cellular processes are essential: appropriate epithelial adhesion, hyphal extension and invasion, high levels of ECE1 transcription, proper Ece1 processing, ending in candidalysin secretion and accumulation in the invasion pocket. If any of such
Selene Mogavero   +13 more
wiley   +1 more source

Nanotechnology‐Based Strategies to Evaluate and Counteract Cancer Metastasis and Neoangiogenesis

open access: yesAdvanced Healthcare Materials, Volume 10, Issue 10, May 19, 2021., 2021
Nanomaterials can be used as detection and therapeutic agents to combat cancer metastasis and angiogenesis, owing to their unique characteristics which allow tailored and tunable functions. Abstract Cancer metastasis is the major cause of cancer‐related morbidity and mortality.
Özlem Şen   +2 more
wiley   +1 more source

Corticosteroid delivery using oral mucosa equivalents for the treatment of inflammatory mucosal diseases

open access: yesEuropean Journal of Oral Sciences, Volume 129, Issue 2, April 2021., 2021
Abstract Oral lichen planus (OLP) is an immune‐mediated disease of the oral mucosa with idiopathic aetiology. It is frequently treated with topical corticosteroids (applied as gels, mouthwashes, or sprays); however, the mucosal exposure times of topical corticosteroids are short because of removal by the constant flow of saliva and mechanical forces ...
Zulfahmi Said   +4 more
wiley   +1 more source

Facilitated Buccal Insulin Delivery via Hydrophobic Ion-Pairing Approach: In vitro and ex vivo Evaluation

open access: yesInternational Journal of Nanomedicine, 2021
Santosh Bashyal,1 Jo-Eun Seo,1 Taekwang Keum,1,2 Gyubin Noh,1,2 Shrawani Lamichhane,1,2 Jeong Hwan Kim,1,2 Chang Hyun Kim,3 Young Wook Choi,3 Sangkil Lee1,2 1College of Pharmacy, Keimyung University, Daegu, Republic of Korea; 2Center for Forensic ...
Bashyal S   +8 more
doaj  

Cytokine-Mediated Inflammation in the Oral Cavity and Its Effect on Lipid Nanocarriers

open access: yesNanomaterials, 2021
Topical drug administration to the oral mucosa proves to be a promising treatment alternative for inflammatory diseases. However, disease-related changes in the cell barrier must be considered when developing such delivery systems.
Carolin Tetyczka   +8 more
doaj   +1 more source

IL-29 Enhances CXCL10 Production in TNF-α-stimulated Human Oral Epithelial Cells [PDF]

open access: yesImmunological Investigations, 2017
Interleukin-29 (IL-29) is a cytokine belonging to the type III interferon family. It was recently detected in the gingival crevicular fluid of periodontitis patients.
Y. Hosokawa   +4 more
semanticscholar   +2 more sources

Examination of Effective Buccal Absorption of Salmon Calcitonin Using Cell-Penetrating Peptide-Conjugated Liposomal Drug Delivery System

open access: yesInternational Journal of Nanomedicine, 2022
Taekwang Keum,1,2,* Gyubin Noh,1,2,* Jo-Eun Seo,1 Santosh Bashyal,1,2 Dong Hwan Sohn,1 Sangkil Lee1,2 1College of Pharmacy, Keimyung University, Daegu, Republic of Korea; 2Center for Forensic Pharmaceutical Science, Daegu, Republic of Korea&ast ...
Keum T   +5 more
doaj  

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