Results 101 to 110 of about 113,271 (309)
Genetic Dissection of Trabecular Bone Structure with Mouse Intersubspecific Consomic Strains
G3: Genes, Genomes, Genetics, 2017 Trabecular bone structure has an important influence on bone strength, but little is known about its genetic regulation. To elucidate the genetic factor(s) regulating trabecular bone structure, we compared the trabecular bone structures of two ...
Taro Kataoka +4 more
doaj +1 more source
Advanced Science, EarlyView.A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu +13 more
wiley +1 more source
Real-time microdamage and strain detection during micromechanical testing of single trabeculae
, 2007 For the assessment of local deformations, we recently combined mechanical testing of trabecular bone with high-speed photography. In a previous study on cuboids of human vertebral trabecular bone we found strained trabeculae to whiten, and scanning ...
Hansma, Paul K. +5 more
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Qualitative changes in fetal trabecular meshwork fibers at the human iridocorneal angle
, 2013 We examined a series of changes that occur in the trabecular meshwork fibers of human eyes during fetal development at 12-30 weeks of gestation.
Murakami, Gen +5 more
core +1 more source
NAT10‐Mediated ac4C Modification of circANKRD12 Reprograms the Tumor Microenvironment
Advanced Science, EarlyView.NAT10‐dependent acetylation of circANKRD12 drives translation of the circANKRD12_354aa protein, which binds HDAC2 to stabilize c‐Myc via deubiquitination, promoting multiple myeloma (MM) cell proliferation. Concurrently, the circANKRD12‐HDAC2 axis suppresses H3ac‐mediated transcription of IFN‐γ, TNF‐α, and GZMB in NK cells, leading to NK cell ...
Jiale Zhang +8 more
wiley +1 more source
Oxidative damage and autophagy in the human trabecular meshwork as related with ageing.
PLoS ONE, 2014 Autophagy is an intracellular lysosomal degradation process induced under stress conditions. Autophagy also plays a major role in ocular patho-physiology. Molecular aging does occur in the trabecular meshwork, the main regulator of aqueous humor outflow,
Alessandra Pulliero +5 more
doaj +1 more source
Reconstruction of trabecular tissue from human trabecular cells as a multicellular spheroid.
Acta medica Okayama, 1997 To understand the development of the trabecular meshwork of the eye, floating cellular aggregates (multicellular spheroids) were formed from human trabecular cells in a non-adherent environment of culture and incubated for up to one month. Dissociated trabecular cells formed multicellular spheroids within one day in the non-adherent environment, and ...
Matsuo, Toshihiko, Matsuo, Nobuhiko
openaire +3 more sources
Advanced Science, EarlyView.CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu +12 more
wiley +1 more source
Advanced Science, EarlyView.Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv +13 more
wiley +1 more source
, 2012 Joo Hyung Lee,1 Keyoung Jin Chun,2 Han Sung Kim,3 Sang Ho Kim,4 Paul Han,3 Yongtae Jun,1 Dohyung Lim11Department of Mechanical Engineering, Sejong University, Seoul, South Korea; 2Gerontechnology Research Group, Korea Institute of Industrial Technology ...
Han P +6 more
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