Results 81 to 90 of about 113,271 (309)

Trabecular architecture in the sciuromorph femoral head: allometry and functional adaptation

Zoological Letters, 2018
Background Sciuromorpha (squirrels and close relatives) are diverse in terms of body size and locomotor behavior. Individual species are specialized to perform climbing, gliding or digging behavior, the latter being the result of multiple independent ...
Maja Mielke, Jan Wölfer, Patrick Arnold, Anneke H. van Heteren, Eli Amson, John A. Nyakatura   +5 more
doaj   +1 more source

FGF 23 and trabecular microarchitecture [PDF]

Osteoporosis International, 2019
n ...
Minisola S., Colangelo L., Cipriani C., Pepe J.   +3 more
openaire   +3 more sources

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

Model-Independent 3D Descriptors of Vertebral Cancellous Bone Architecture

Journal of Osteoporosis, 2010
High-resolution micro computed tomography has enabled measurement of bone architecture derived from 3D representations of cancellous bone. Twenty-eight vertebral bodies were obtained from four embalmed male cadavers.
Ian H. Parkinson, Danielle Forbes, Peter Sutton-Smith, Nicola L. Fazzalari   +3 more
doaj   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

uCT images and mechanical test data for demineralised and deproteinised trabecular bone samples.

, 2018
Nineteen (n=19) bovine trabecular bone samples were scanned before chemical treatment by using Skyscan at high resolution (17.22 µm). The chemical treatment was to either demineralise or deproteinise the samples.
Pankaj, Pankaj, Wallace, Robert, Xie, Shuqiao   +2 more
core   +1 more source

Effect of trabecular bone loss on cortical strain rate during impact in an in vitro model of avian femur

BioMedical Engineering OnLine, 2006
Background Osteoporotic hip fractures occur due to loss of cortical and trabecular bone mass and consequent degradation in whole bone strength. The direct cause of most fractures is a fall, and hence, characterizing the mechanical behavior of a whole ...
Gefen Amit, Reich Tal
doaj   +1 more source

Cortical unlike trabecular bone loss is not associated with vascular calcification progression in CKD patients

BMC Nephrology, 2020
Background Vascular calcification progression has been associated with the loss of trabecular bone in chronic kidney disease (CKD) patients. There are few data evaluating the relationship between cortical bone loss and vascular calcification in this ...
Larissa R. Costa, Aluizio B. Carvalho, Amandha L. Bittencourt, Carlos E. Rochitte, Maria Eugênia F. Canziani   +4 more
doaj   +1 more source