Results 81 to 90 of about 181,991 (355)

Deficits in trabecular bone microarchitecture in young women with Type 1 diabetes mellitus [PDF]

, 2015
Context: The pathophysiological mechanism of increased fractures in young adults with Type 1 Diabetes Mellitus (T1DM) is unclear. Objective: Case:control study of trabecular bone microarchitecture and vertebral marrow adiposity in young women with ...
Al-Daghri, Almeida, Amiel, Baroncelli, Baxter, Benjamin, Bereket, Botolin, Bredella, Bredella, Brismar, Chamberlain, Dai, Dhaliwal, Donaldson, Dunger, Fazeli, Fazeli, Forsén, Genant, Gevers, Giustina, Goettsch, Govan, Guler, Hothersall, Issever, Justesen, Kawai, Li, Martin, McComb, Menagh, Miller, Naressi, Neumann, Nicodemus, Patsch, Qvist, Rosen, Santos, Schellinger, Shen, Slade, Svoren, Vanhamme, Vestergaard, Wagegg, Wędrychowicz, Zemel   +49 more
core   +1 more source

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Model-Independent 3D Descriptors of Vertebral Cancellous Bone Architecture

Journal of Osteoporosis, 2010
High-resolution micro computed tomography has enabled measurement of bone architecture derived from 3D representations of cancellous bone. Twenty-eight vertebral bodies were obtained from four embalmed male cadavers.
Ian H. Parkinson, Danielle Forbes, Peter Sutton-Smith, Nicola L. Fazzalari   +3 more
doaj   +1 more source

Sampling trabecular meshwork using TrabEx+

BMC Ophthalmology, 2021
Background To report sampling of the trabecular meshwork using the TrabEx+ (MicroSurgical Technology, Redmond, Washington, USA) device in ab interno trabeculectomy.
Vipul Ramjiani, Hardeep-Singh Mudhar, Thomas Julian, Graham Auger   +3 more
doaj   +1 more source

Deficiency of annexins A5 and A6 induces complex changes in the transcriptome of growth plate cartilage but does not inhibit the induction of mineralization [PDF]

, 2009
Initiation of mineralization during endochondral ossification is a multistep process and has been assumed to correlate with specific interactions of annexins A5 and A6 and collagens.
Anderson, Anja Niehoff, Balcerzak, Balcerzak, Belluoccio, Bent Brachvogel, Berendes, Blumbach, Brachvogel, Brachvogel, Brachvogel, Bradford, Budde, Christian Frie, Collett, Damazo, Daniele Belluoccio, DiCesare, Ernst Pöschl, Friedericke Pausch, Genge, Genge, Gerke, Girkontaite, Haut Donahue, Hawkins, Hazarika, Hikiji, Hofmann, Ivan Grskovic, John F Bateman, Julia Etich, Karsenty, Karsenty, Kim, Kirsch, Kirsch, Kirsch, Koopman, Kwan, Ling, Livak, Morgan, Murshed, Pfaffl, Rety, Romeis, Sabrina Rosenbaum, Schmitz, Srivastava, Srivastava, Stephen E Moss, Ursula Schlötzer-Schrehardt, Van Gelder, White   +54 more
core   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Prolonging disuse in aged mice amplifies cortical but not trabecular bones’ response to mechanical loading [PDF]

, 2017
Objective: Short-term neurectomy-induced disuse (SN) has been shown to restore load responses in aged mice. We examined whether this restoration was further enhanced in both cortical and trabecular bone by simply extending the SN. Methods: Following load:
Chenu, C, Collinson, R S, De Souza, R, Javaheri, B, Lee, P D, Pitsillides, A A, Shefelbine, S   +6 more
core   +1 more source

Melt Electrowriting High Resolution Poly(ethylene‐co‐vinyl acetate) Scaffolds for Soft Tissue Engineering

Advanced Healthcare Materials, EarlyView.
This work pioneers melt electrowriting (MEW) of polyethylene vinyl acetate (PEVA) to fabricate ultra‐compliant, high‐resolution scaffolds. By integrating microscale precision with soft tissue‐like biomechanics, PEVA overcomes stiffness‐driven limitations of conventional MEW polymers, establishing a mechanically biomimetic platform for soft tissue ...
Finn Snow, Darcy De Rauch, Lilith Mabel Caballero Aguilar, Darcy Millett, Jasley Wilding McBride, David R Nisbet, Magdalena Kita, Elena Pirogova, Robert Michail Ivan Kapsa, Anita Quigley   +9 more
wiley   +1 more source

Effect of trabecular bone loss on cortical strain rate during impact in an in vitro model of avian femur

BioMedical Engineering OnLine, 2006
Background Osteoporotic hip fractures occur due to loss of cortical and trabecular bone mass and consequent degradation in whole bone strength. The direct cause of most fractures is a fall, and hence, characterizing the mechanical behavior of a whole ...
Gefen Amit, Reich Tal
doaj   +1 more source