Results 91 to 100 of about 67,374 (288)

Ocular Findings as the Most Striking Manifestation of a SMAD3 Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Loeys‐Dietz syndrome (LDS) is a heritable connective tissue disorder with variable expressivity. It is a multisystemic condition mainly characterized by a propensity for arterial aneurysms and dissections, skeletal manifestations, hypertelorism, bifid uvula, craniosynostosis, and cutaneous features.
Noémie Villeneuve‐Cloutier, Christie A Boswell‐Patterson, Lucas Bronicki, Krista M. Vincent, Kalin Wilk, Andrea C. Yu, Gail E. Graham, Julie Richer   +7 more
wiley   +1 more source

Review Of Applied Mathematical Models For Describing The Behaviour Of Aqueous Humor In Eye Structures

International Journal of Applied Mechanics and Engineering, 2015
In the paper, currently used methods for modeling the flow of the aqueous humor through eye structures are presented. Then a computational model based on rheological models of Newtonian and non-Newtonian fluids is proposed. The proposed model may be used
M. Dzierka, P. Jurczak
doaj   +1 more source

Helmeted hornbill cranial kinesis: Balancing mobility and stability in a high‐impact joint

The Anatomical Record, EarlyView.
Abstract Prokinesis—in which a craniofacial joint allows the rostrum to move relative to the braincase—is thought to confer diverse advantages in birds, mostly for feeding. A craniofacial joint would, however, be a weak link if cranial stability is important. Paradoxically, we have identified a craniofacial joint in helmeted hornbills (Rhinoplax vigil),
Mike Schindler, Benjamin Flaum, Armita Razieh Manafzadeh, Viktoriia Kamska, Kanmani Chandra Rajan, Maria Jose Robles Malagamba, Ruien Hu, Daniel Baum, Mason N. Dean   +8 more
wiley   +1 more source

Development of the occipitopetrosal junctions: A histological study using human fetuses

The Anatomical Record, EarlyView.
Abstract The temporal bone petrosa is connected to the occipital bone at two sites: one junction with the basilar part (medial junction) and another with the lateral part (lateral junction). Using histological specimens from 45 human fetuses (approximately 7–39 weeks of gestational age or GA), we aimed to describe possible changes in histology and ...
Ai Hirano‐Kawamoto, Yohei Honkura, Chun‐Ai Li, Samuel Verdugo‐López, Gen Murakami, Jose Francisco Rodríguez‐Vázquez, Yukio Katori   +6 more
wiley   +1 more source

Structurally and Functionally Adaptive Biomimetic Periosteum: Materials, Fabrication, and Construction Strategies

Exploration, EarlyView.
Schematic illustration of structural and functional biomimicry. The upper part shows BP with various structures such as monolayered, surface‐microstructural, bilayered and multilayered. The bottom part exhibits BP with different functions including immune regulation, drugs/cells/factors/ions loading, as well as bioelectrical stimulation and ...
Yuhan Du, Yujie Liu, Yuanchi Zhang, Yangyi Nie, Zili Xu, Ling Qin, Wei Zhang, Yuxiao Lai   +7 more
wiley   +1 more source

Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm’s canal endothelial cells

Scientific Reports, 2016
Ripasudil hydrochloride hydrate (K-115), a specific Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor, was the first ophthalmic solution developed for the treatment of glaucoma and ocular hypertension in Japan.
Yoshio Kaneko, Masayuki Ohta, Toshihiro Inoue, K. Mizuno, Tomoyuki Isobe, S. Tanabe, H. Tanihara   +6 more
semanticscholar   +1 more source

Automated Acetabular Defect Reconstruction and Analysis for Revision Total Hip Arthroplasty: A Computational Modeling Study

Journal of Orthopaedic Research, Volume 43, Issue 7, Page 1315-1324, July 2025.
ABSTRACT Revision total hip arthroplasty (rTHA) involving large acetabular defects is associated with high early failure rates, primarily due to cup loosening. Most acetabular defect classification systems used in surgical planning are based on planar radiographs and do not encapsulate three‐dimensional geometry and morphology of the acetabular defect.
Daniel Hopkins, Stuart A. Callary, L. Bogdan Solomon, Peter V. S. Lee, David C. Ackland   +4 more
wiley   +1 more source

Harmonizing NAD+ metabolism with CeMOF nanozyme to orchestrate intraocular pressure modulation for glaucoma treatment

VIEW, EarlyView.
Our findings demonstrate that NAD+ metabolism dysregulation contributes to elevated intraocular pressure in glaucoma. Supplementation with NAD+ precursors reduces IOP by alleviating oxidative stress, cellular senescence, and extracellular matrix deposition.
Youjia Zhang, Ming Chen, Yi Tian, Bo Qin, Xiaoxiao Chen, Yiwen Zhou, Jinhai Huang, Mei Yang, Xinghuai Sun, Yuan Lei, Yuhong Chen   +10 more
wiley   +1 more source

Vision at high latitudes: High sensitivity without specific boreal adaptations in photoreception in reindeer (Rangifer tarandus L.)

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The light climate at high latitudes, in particular the extended twilight of winter and the reduced diel variation in light level in midsummer and midwinter, potentially constrains visual function and the synchronisation of temporal organisation in polar species. In this
Nicholas J. C. Tyler, Robert A. E. Fosbury, David Hazlerigg, Christopher Hogg   +3 more
wiley   +1 more source

Restoration of Aqueous Humor Outflow Following Transplantation of iPSC-Derived Trabecular Meshwork Cells in a Transgenic Mouse Model of Glaucoma

Investigative Ophthalmology and Visual Science, 2017
Purpose Primary open-angle glaucoma (POAG) is particularly common in older individuals and associated with pathologic degeneration of the trabecular meshwork (TM).
Wei Zhu, Ankur Jain, O. Gramlich, B. Tucker, V. Sheffield, M. Kuehn   +5 more
semanticscholar   +1 more source